Objective. Rare case presentation of thyroid cartilage variation causing globus sensation and dysphagia. Method. Case report and review of the literature concerning thyroid cartilage variant of clinical significance. Results. Middle-aged male patient presented with globus sensation and painful swallow without previous injury of the larynx. Clinical examination and diagnostic procedures revealed...

Myocardial perfusion SPECT is one of the most common imaging techniques performed in nuclear medicine departments. To avoid misleading interpretation, it is necessary to address the quality control and technical problems. The truncation artifact occurs when the patient size is large relative to the field of view of the camera, causing false perfusion defects in the LV myocardium, misinterpreted...

BACKGROUND AND OBJECTIVES Nemaline myopathy may be caused by pathogenic variants in the TPM3 gene and is then called NEM1. All previously identified disease-causing variants are point mutations including missense, nonsense and splice-site variants. The aim of the study was to identify the disease-causing gene in this patient and verify the NM diagnosis. METHODS Mutation analysis methods inclu...

Few aspects of biology are linked to so many evolutionary conflicts as sperm production and fertilization. Segregation distortion and maternal inheritance of cytoplasmic genes, causing maladapted males, are common sources of variation in the competitive ability of sperm, leading males to vary in their intrinsic fertility. Here, I theoretically analyze the effect of such variation in male intrin...

Major histocompatibility complex (MHC) variation is a key determinant of susceptibility and resistance to a large number of infectious, autoimmune and other diseases. Identification of the MHC variants conferring susceptibility to disease is problematic, due to high levels of variation and linkage disequilibrium. Recent cataloguing and analysis of variation over the complete MHC has facilitated...

in order to study genetic variation and relationship between traits, 615 accessions of local bread wheat from wheat collection of national plant gene bank of iran were evaluated. seeds of the accessions were planted in 2.5 meter long rows in an observatory design and 17 agro-morphological traits were measured. grain yield of 5 spikes, number of tillers and number of seeds per spike were of high...