We examined two hypotheses about the developmental relation between substance abuse and individual differences in desistance from antisocial behavior during young adulthood. The "snares" hypothesis posits that substance abuse should result in time-specific elevations in antisocial behavior relative to an individual's own developmental trajectory of antisocial behavior, whereas the "launch" hypo...

BACKGROUND There are few studies with an assessment of the levels of cytokines or neuropeptides as correlates of pain and pain relief in patients with painful joint diseases. Our objective was to assess whether improvements from baseline to 2-months in serum cytokine, chemokine and substance P levels were associated with clinically meaningful pain relief at 2-months post-injection in patients w...

In two samples of Flemish secondary school students, co-occurrence of different types of substance use was observed: smoking was associated with marijuana use in Sample 1 (n = 597) and alcohol consumption in Sample 2 (n = 403). It was investigated whether social-cognitive determinants of these behaviours were also associated. Low to medium correlations were observed. Confirmatory factor analyse...

Background: Inattention to symptoms of mental disorders and substance abuse in patients with HIV/AIDS and other at-risk groups, may lead to irreversible damages. The purpose of this study was to compare the psychopathological dimensions in substance abusers with and without HIV/AIDS and healthy matched groups. Methods: In a cross-sectional and analytical study, selected samples (by available, c...

Solution x-ray scattering using synchrotron radiation as an x-ray source has been used to study the solution structure of calmodulin complexed with substance P, a undecapeptide neurotransmitter. The x-ray data indicate that the complex has a compact globular structure, the formation of which is dependent upon the binding of Ca2+ to calmodulin. In the Ca(2+)-saturated condition, the radius of gy...

This compendium summarizes the fusion enthalpies of approximately 1000 new measurements. A group additivity method developed to estimate the total phase change entropies and enthalpies of organic solids is updated, applied to the new data and the results are compared. The uncertainties associated ccepted 14 May 2009 vailable online 23 May 2009

Previous discovery systems have successfully rediscovered known scientific laws . However, they have addressed only limited parts of the empirical discovery task . In this paper we introduce an integrated discovery system (IDS) which addresses many issues of empirical discovery. IDS operates in three stages : taxonomy formation, qualitative discovery, and quantitative discovery. We focus on the...

BACKGROUND Historically, smoking cessation was thought to negatively impact substance use outcomes among smokers who use other substances. We sought to synthesize recent reports on this association. METHODS Google Scholar, PubMed, and Cinahl were searched for studies published from 2006 to March 29, 2016 that reported impact of smoking cessation treatment or quitting smoking on substance use ...

The effects of climate change on the taste and textural attributes of foods remain largely unknown, despite much public interest. On the basis of 30-40 years of records, we provide evidence that the taste and textural attributes of apples have changed as a result of recent global warming. Decreases in both acid concentration, fruit firmness and watercore development were observed regardless of ...