BACKGROUND Depression and anxiety are correlated with greater nicotine dependence, smoking persistence, and relapse back to smoking after a quit attempt. Menthol cigarette smoking, which is prevalent in young adults, is associated with nicotine dependence, progression to regular smoking, and worse cessation outcomes than non-menthol smoking. Few have established a link between menthol tobacco u...

Carvedilol is administered as a racemic mixture of the R(+)- and S(-)-enantiomers, although it was demonstrated that the two enantiomers exhibit different pharmacological effects and stereoselective pharmacokinetics. The aim of this study was the evaluation of several native and derivatized cyclodextrines as chiral selectors for the separation of carvedilol enantiomers. Stereoselective interact...

In order to more fully understand why individuals smoke menthol cigarettes, it is important to understand the perceptions held by youth and adults regarding menthol cigarettes. Perceptions are driven by many factors, and one factor that can be important is marketing. This review seeks to examine what role, if any, the marketing of menthol cigarettes plays in the formation of consumer perception...

A great number and variety of homogeneous lanthanide catalysts are now used in industry and academia as low-cost, low-toxicity, Lewis acidic, and coordination catalysts. In the search for new asymmetric catalysts, chiral C3-symmetric complexes are emerging as interesting competitor systems to the ubiquitous C2-symmetric systems. [2] Trivalent lanthanide cations are obvious candidates for the de...

Chiral chelated lithium amides were designed and synthesized. Studies have been done to explore the use of these lithium amides or their corresponding amines for enantioselective reactions such as deprotonation of prochiral cyclic ketones, kinetic resolution of racemic 2-substituted cyclohexanones by deprotonation, regioselective deprotonation of optically active 3-keto steroids, alkylation of ...

A chiral tetrathiafulvalene (1) bearing a binaphtholdimethylene moiety on one side, an ethylenedithio substituent on the other side, is prepared from atropoisomeric (R)-, (S)and racemic (R,S)-binaphthol. Its oxidation potential (0.49 V vs. SCE) allows for its oxidation with TCNQF4. Crystal structures of the neutral racemic (R,S)-1 and enantiopure (R)-1 were determined together with those of the...

OBJECTIVE To determine what the tobacco industry knew about menthol's relation to smoking cessation behaviour. METHODS A snowball sampling design was used to systematically search the Legacy Tobacco Documents Library (LTDL) (http://legacy.library.ucsf.edu) between 15 May to 1 August 2010. Of the approximately 11 million documents available in the LTDL, the iterative searches returned tens of ...

The origin of biomolecular homochirality continues to be one the most fascinating aspects prebiotic chemistry. Various amplification strategies for chiral compounds enhance a small preference have been reported, but none these involves phosphorylation, nature's essential chemical reactions. Here we present simple and robust concept phosphorylation-based amines amino acids in water. By exploitin...