The objective of our work was to evaluate the effect of sertraline hydrochloride on serum levels of leptin and sexual function in patients with premature ejaculation (PE). A total of 124 patients with a history of PE at least 6 months, aged 20-50 years, were treated with sertraline hydrochloride. One hundred and four age-matched normal males without a history of PE were included control subject...

BACKGROUND Several recent studies have investigated the therapeutic role of phosphodiesterase type 5 (PDE5) inhibitors in premature ejaculation (PE) used in the treatment of erectile dysfunction. OBJECTIVES In the present research, the efficacy of paroxetine alone and paroxetine plus tadalafil was compared in patients referred because of premature ejaculation. PATIENTS AND METHODS This quas...

PURPOSE Premature ejaculation/rapid ejaculation is a common but incompletely understood male sexual dysfunction. The purposes of this review are to 1) raise awareness of the prevalence and characteristics of PE/RE, its impact on the male and his partner, and the lack of approved medications indicated for its treatment, 2) encourage dialogue about PE/RE between physicians and patients, and 3) st...

Meta-analyses of antidepressant treatment in young people have relied exclusively on clinicianrated measures of depressive symptoms. These symptom-based measures may not capture other important correlates of well-being, such as quality of life, functioning, global mental health or well-being, or self-reported depressive symptoms. Results of the present metaanalysis, based on 8 placebo-controlle...

as contained in application WO8903692) Compositions useful in the treatment of disturbances of appetite, disturbances of mood, or both, associated with premenstrual syndrome, as well as methods of use therefor. The compositions include serotoninergic drugs, such as d-fenfluramine and fluoxetine. Claims 1. Use of one or more serotonin-mediated neurotransmission enhancing drugs for the manufactur...

Over the past two decades our understanding of ejaculatory dysfunction has evolved from the initial premise that these conditions were almost exclusively due psychological factors to a new understanding. We now understand that men with lifelong premature ejaculation may have an underlying genetic predisposition to rapid ejaculation and that men with acquired premature ejaculation may have, in a...

OBJECTIVES We recommend a new kind of spray made from eight kinds of traditional Chinese medicine, we aimed to investigate the safety and clinical efficacy of combined traditional Chinese medicine spray (TCMS) with premature ejaculation desensitization therapy (PEDT) for the treatment of primary premature ejaculation (PPE). METHODS A total of 90 patients with PPE were randomly assigned to rec...

background: premature ejaculation (pe) is the most common sexual disorder in men and studies reported prevalence up to 30% (1, 2). pe is not a life-threatening medical condition but it influences the quality of life (qol). objectives the aim of this study was to compare the efficiency, and safety of alpha blocker drugs in the treatment of patients with premature ejaculation (pe). additionally w...

OBJECTIVE To assess the effectiveness of dapoxetine in the treatment of premature ejaculation. METHODS Both English and Chinese studies involving men with prematrue ejaculation who were treated with dapoxetine from the Cochrane Library, MEDLINE, EMBASE and CNKI, CBM, VIP between 1979 and 2009.were included in the randomized controlled trials (RCTs) and the data processed by RevMan. RESULTS ...