Johnson and his colleagues at CME Group for useful comments. I acknowledge financial support from CME Group. This article presents my views, conclusions and recommendations and are not necessarily those of CME Group. The opinions expressed in this study are those of the authors and do not necessarily reflect those of EDHEC Business School.

The noisy dynamics of chemical systems is commonly studied using either the chemical master equation (CME) or the chemical Fokker-Planck equation (CFPE). The latter is a continuum approximation of the discrete CME approach. It has recently been shown that for a particular system, the CFPE captures noise-induced multistability predicted by the CME. This phenomenon involves the CME's marginal pro...

Continuing medical education (CME) of physicians, a life-long commitment, is one of the foundations of medical professionalism. This article outlines CME objectives and the regulatory framework through which it is delivered, addressing the safeguards against commercial intrusion and the preservation of scientific objectivity. The article also includes a brief review of the principles of adult l...

OBJECTIVE The study was conducted to evaluate the effects of different methionine (Met) sources on production performance, reproduction performance, egg quality and serum biochemical indices in broiler breeders. METHODS After receiving a basal diet (containing 0.25% Met) for a 2-wk pretreatment period, a total of 360 39-wk-old Lingnan yellow broiler breeders were randomly allocated to four tr...

INTRODUCTION There is a need to provide practicing physicians with training on the recognition and management of intimate partner violence (IPV). Online continuing medical education (CME) could help meet this need, but there is little information on the costs and effectiveness of promoting online CME to physicians. This lack of information may discourage IPV training efforts and the use of onli...

This experimental study was designed to clarify the relationship between cardiomyocyte apoptosis and tumour necrosis factor-alpha (TNF-α) expression, and confirm the effect of TNF-α on cardiac dysfunction after coronary microembolization (CME) in mini-pigs. Nineteen mini-pigs were divided into three groups: sham-operation group (n = 5), CME group (n = 7) and adalimumab pre-treatment group (n = ...

INTRODUCTION Clinical trial data can be presented in ways that exaggerate treatment effectiveness. Physicians consider therapy more effective, and may be more likely to make inappropriate practice changes, when data are presented in relative terms such as relative risk reduction rather than in absolute terms such as absolute risk reduction and number needed to treat. Our purpose was to determin...

Coronary microembolization (CME) is a common complication of percutaneous coronary intervention (PCI) for acute coronary syndrome. It leads to myocardial apoptosis and cardiac dysfunction. Nicorandil pretreatment can prevent PCI-related myocardial injury and reduce the incidence of no- or slow-reflow phenomena. This cardioprotective effect is probably attributable to the suppression of CME-indu...

BACKGROUND Cordyceps militaris has been used in traditional medicine to treat numerous diseases and has been reported to possess both antitumor and immunomodulatory activities in vitro and in vivo. However, the pharmacological and biochemical mechanisms of Cordyceps militaris extract (CME) on macrophages have not been clearly elucidated. In the present study, we examined how CME induces the pro...

In this paper, a generic self-similar flux rope model is proposed to probe the internal state of CMEs in order to understand the thermodynamic process and expansion of CMEs in interplanetary space. Using this model, three physical parameters and their variations with heliocentric distance can be inferred based on coronagraph observations of CMEs’ propagation and expansion. One is the polytropic...