نتایج جستجو برای: concentration response curve
تعداد نتایج: 1418229 فیلتر نتایج به سال:
Abbreviations: AE: Adverse Event; AUC: Area under Plasma Concentration–time Curve; AUCinf: Area under Plasma Concentration-time Curve from Time Zero Extrapolated to Infinite Time; AUClast: Area under Plasma Concentration–time Curve from Time Zero to the Time of the Last Quantifiable Concentration; BMI: Body Mass Index; CI: Confidence Interval; Cmax: Maximum Plasma Concentration; CRU: Clinical R...
A number of mathematical models have been tested for their suitability in representing the dose response curve of a specific assay of the hormone human placental lactogen (HPL).(1)A new equation Y = B[0.14 + 1/[1 + C log [1 + exp[X - D]]] where Y is the percentage activity or counts bound to the antibody and X is the HPL concentration is proposed as representing the overall shape of the curve. ...
It is debated whether exercise-induced ROS production is obligatory to cause adaptive response. It is also claimed that antioxidant treatment could eliminate the adaptive response, which appears to be systemic and reportedly reduces the incidence of a wide range of diseases. Here we suggest that if the antioxidant treatment occurs before the physiological function-ROS dose-response curve reache...
This paper has two objectives. First, it establishes a model for scoring the access to pharmaceutical services. Second, it develops a model for measuring socioeconomic indicators independent of the time and place of study. These two measures are used for measuring equity in access to pharmaceutical services using concentration curve. We prepared an open-ended questionnaire and distributed it to...
There is great need to express the impacts of chemicals found in the environment in terms of effects from alternative chemicals of interest. Methods currently employed in fields such as life-cycle assessment, risk assessment, mixtures toxicology, and pharmacology rely mostly on heuristic arguments to justify the use of linear relationships in the construction of "equivalency factors," which aim...
PURPOSE Paclitaxel and carboplatin are frequently used in advanced ovarian cancer following cytoreductive surgery. Threshold models have been used to predict paclitaxel pharmacokinetic-pharmacodynamics, whereas the time above paclitaxel plasma concentration of 0.05 to 0.2 micromol/L (t(C > 0.05-0.2)) predicts neutropenia. The objective of this study was to build a population pharmacokinetic-pha...
Reaching an electricity system which is both economically efficient and environmentally friendly is motivating countries to design and execute different types of TOU demand response programs. But there are certain deficiencies which prevent these programs to effectively modify the load shape. Smart grid as a means could help the electricity system to reach the highest demand side management ...
Rapid development in nuclear industry and medical applications involving radiation sources would increase the potential of exposure to the ionizing radiation. Due to the harmful effects of radiation exposure on the health of radiation workers, rapid dose estimation of the overexposed victims with high accuracy is quite important in taking appropriate medical treatment plan. Biological dosimetry...
A rapid quantitative microenzyme-linked immunosorbent assay for the detection of immunoglobulin G antibodies to tetanus toxoid is described. The assay is performed in 2.5 h and detects antibody levels of between 0.1 and 6 U/ml. Quantitation of the antibody concentration is unique in that multiple serum dilutions are tested on a single patient, the results are plotted as an antibody dilution cur...
the history of plant’s used for mankind is as old as the start of humankind. initially, people used plants for their nutritional proposes but after the discovery of medicinal properties, this natural ?ora became a useful source of disease cure and health improvement across various human communities. berberis vulgaris is one of the medicinal plants used in iranian traditional medicine. berberis ...
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