OBJECTIVES The aim of the study was to determine the extent and nature of consanguinity in the Qatari population and its effects on common adult diseases. SUBJECTS AND METHODS The study was conducted in urban and semi-urban areas of Qatar between October 2004 and May 2005. The total sample of 1,050 married Qatari females 15 years of age and over were approached for study. The degree of consan...

Fumaric aciduria is a rare autosomal recessive metabolic disease which is characterized with excessive fumaric acid exretion in urine. In the prenatal period, polyhydramniosis, intrauterine growth retardation, enlarged brain ventricles and brain anomalies are observed. Growth and development failure, hypotonia, seizures and brain atrophy are the common characteristics of patients with fumarase ...

objectives: the prevalence of consanguineous marriage is about 30 % in iran and this can increase the probability of incidence of genetic impairments such as hearing impairments. hearing impairment in comparison with other hereditary disorders is the most incident. the purpose of this survey is to identify the prevalence of consanguinity among the parents of sensoryneural hearing impaired stude...

Introduction: The occurrence of consanguineous marriages has been common in the Arab populations due to socio-cultural factors. Genetic diseases are rare overall population, but their frequency unusually increases as prevalence increases. aim our pilot study was investigate extent consanguinity and its effects on non-communicable genetic diseases, Emirati population. Methodology: This research ...

The rarity of consanguineous marriage in much of the industrialized world, and the current restriction or outright prohibition of first-cousin unions in a majority of US states and in East Asian countries such as China, North and South Korea and the Philippines, has led many commentators to overlook the fact that the Out-of-Africa migration some 60,000–70,000 years ago had been undertaken by qu...

This report concerns two families in which the index patients are sporadic cases of a benign form of muscular dystrophy. In both families the sisters of the patients have married a close relative. The respective risks for a child of these consanguineous marriages being affected with either X linked Becker muscular dystrophy or autosomal recessive limb girdle muscular dystrophy is calculated usi...

The first man reported in the world literature exhibiting habitual quadrupedal locomotion was discovered by a British traveler and writer on the famous Bagdad road near Havsa/Samsun on the middle Black Sea coast of Turkey (Childs, 1917). The man most probably belonged to a Greek family, since the region of Havsa was populated by Greek people during the time of the Ottoman Empire. He possibly be...

Introduction The estimation of genetic risks to the offspring of consanguineous marriages, especially those of first cousins, has been exhaustively studied in the literature. Even so the subject still remains controversial, as shown by the results of a recent inquiry performed among medical geneticists and genetic counsellors in the United States by Bennett et al. (1999). In fact, analysing the...