Oral cavity can be used for local drug delivery as in for periodontitis, dental caries or for oral mucosal drug delivery as for alveolar osteitis, analgesia or transmucosal systemic effect as for smoking cessation or delivery of biotechnological products like proteins and peptides. This article gives an overview of basic structure, function, biochemistry, and permeability of the oral cavity. Di...

In recent years, use of biodegradable polymers based nanoparticles has received highinterest in the development of vaccines delivery vehicles. The aim of study was to preparechitosan nanoparticles (CS NPs) for loading Echis carinatus (EC) venom and evaluate theirpotential as an adjuvant and antigen delivery system on a pilot scale. CS NPs were preparedusing ionic gelation method, and their char...

Background & aim: Several factors influence the choice of cesarean section and its increasing rate among pregnant women. It seems that sexual satisfaction after childbirth plays a pivotal role in the selection of delivery mode. This study aimed to describe the experiences of pregnant women regarding postnatal sexual concerns and delivery mode selection. Methods:This conventional qualitative con...

hydrogels are introduced to modem medicine as novel materials suitable for a variety ofbiomedical applications. studying hydrogels as novel biomaterials has become a fast-developingand exciting research field during the last two decades. these interesting biomaterials have found awide range of application including contact lenses, vehicles for drug delivery and scaffold in tissueengineering and...

INTRODUCTION Caesarean delivery remains the most common intraperitoneal surgical procedure in obstetric and gynaecologic practice. Since time immemorial there have been countless efforts to improve the technique of caesarean section. One such innovative breakthrough technique is the Misgav Ladach method of caesarean of section. The objective of this trial was to compare the intraoperative and s...

AIM OF THE STUDY Helical tomotherapy is one of the methods of radiotherapy. This method enables treatment implementation for a wide spectrum of clinical cases. The vast array of therapeutic uses of helical tomotherapy results directly from the method of dose delivery, which is significantly different from the classic method developed for conventional linear accelerators. The paper discusses the...

Abstract Protein coronae formed with nanoparticles confer several useful properties. However, the non‐specific nature of protein corona formation makes it difficult to deliver specific proteins for therapeutic applications. Herein, we report on construction a new type corona, termed binding‐mediated corona. This enables efficient and controllable delivery functional proteins, which is otherwise...

Stereotactic body radiation therapy (SBRT) employs precision target tracking and image-guidance techniques to deliver ablative doses of radiation to localized malignancies; however, treatment with conventional photon beams requires lengthy treatment and immobilization times. The use of flattening filter-free (FFF) beams operating at higher dose rates can shorten beam-on time, and we hypothesize...

In addition to several well-known drug delivery strategies developed to facilitate effective chemotherapy with anticancer agents, some new approaches have been recently established, based on specific effects arising from the applications of ultrasound, magnetic and electric fields on drug delivery systems. This paper gives an overview of newly developed methods of drug delivery to tumors and of...