Our studies demonstrated that Heme oxygenase (HO), in particular, the constitutive HO-2, is critical for a self-resolving inflammatory and repair response in the cornea. Epithelial injury in HO-2 null mice leads to impaired wound closure and chronic inflammation in the cornea. This study was undertaken to examine the possible relationship between HO-2 and the recruitment of neutrophils followin...

QUESTION Corneal abrasion from minor injury to the eye is common in both adults and children. Some of my colleagues prescribe topical nonsteroidal anti-inflammatory drugs (NSAIDs) for analgesia. How safe is this practice? ANSWER Topical ophthalmic NSAIDs are a short-term effective treatment of the pain associated with corneal abrasions in children. Rare but serious complications have been rep...

CASE REPORT A 78-year-old-woman presented with a corneal non-pigmented vascularised tumour of her left eye, of 2 months onset, but with no previous ocular disorders. Surgical excision was performed, and the histopathological study showed the lesion to be an atypical melanocytic nevus of the limbus. DISCUSSION Corneal pigmented lesions tend to occur as a result of conjunctival or sclerocorneal...

Corneal trauma is one of the leading causes of ocular morbidity. This paper aims at providing some practical tips useful for management of corneal wounds.

A 30-year-old man who had laser in situ keratomileusis (LASIK) for myopia 1 year earlier developed a corneal perforation in the left eye from a boa constrictor. The patient presented to the emergency room, and a small corneal perforation just outside the visual axis was diagnosed within the LASIK flap. Cyanoacrylate adhesive was used to close the corneal perforation. The patient went on to full...

OBJECTIVE To determine the corneal injuries pattern. MATERIAL AND METHOD It is a retrospective hospital based analysis of 5504 corneal injuries among the 111781 patients attending King Mahendra Memorial Eye Hospital over a period of 4 years in order to know the lesions pattern for planning purpose. RESULTS Among the corneal lesions, 59.7% were traumatic and 40.3% were non traumatic lesions,...

Introduction: A corneal foreign body is the most common occupational ocular injury that can cause secondary infection or scars on visual axis, decreasing vision. The study aimed to find out practices of wearing protective eye devices in workplace and factors influencing utilization such among patients with (CFB) injury.
 Methods: This cross-sectional was conducted a tertiary hospital Bhakt...

CASE REPORT A 23 years old male with an unremarkable past medical history suffered an injury with a branch of a lemon tree in the right eye two days prior to presentation. The slit-lamp examination showed a central corneal erosion with a white tree-shaped stromal infiltrate and Tyndall +/++ in anterior chamber. Cultivation of corneal scraping was positive for Colletotrichum spp. The patient res...

purpose: to evaluate the demographic data, mechanisms of injury and complications of ocular trauma in patients over 60 year of age. methods: we retrospectively reviewed the medical records of 91 patients older than 60 who were admitted and treated in the ophthalmology department of khalili hospital, between september 2002 and november 2008, due to ocular trauma. data were retrieved from admissi...