In view of the current speculation regarding the possible role of reactive oxygen species (ROS) in apoptosis, both under physiological conditions and in response to chemicals that promote their intracellular formation, the present investigation was undertaken to examine whether DNA fragmentation during oxidative stress results from endonuclease activity (apoptosis) or from direct attack by ROS....

The present work introduces coordinative binding of CuII ions with both amino-functionalized silica nanoparticles (SNs) and green-emitting carbon dots (CDs) as the pregrequisite for CuII-assisted self-assembly CDs at surface SNs. produced composite SNs exhibit stable in time stimuli-responsive green fluorescence derived from assemblage CDs. response is sensitive to complex formation glutathione...

A series of symmetric multidentate Schiff base ligands 1–13 based on the N‚N′-4‚4′-ethylenebiphenylbis-3-methoxysalicylideneimine for used to bind various transition metals detection of K, AgI‚ CuII, Sr II Co II and NiII at trace levels in real-world samples has been synthesized purified and their structures was characterized.

The redox activity of Cu ions bound to the amyloid-β (Aβ) peptide is implicated as a source oxidative stress in context Alzheimer's disease. In order explain efficient cycling between CuII-Aβ (distorted square-pyramidal) and CuI-Aβ (digonal) resting states, existence low-populated “in-between” state, prone bind both oxidation has been postulated. Here, we exploited partial X-ray induced photore...

The assignments structures of the four 1:1 pipemidic acid (pipH)–magnesium(II), calcium(II), zinc(II), and iron(III) complexes, [Mg(pip)(H2O)3(Cl)].6H2O, [Ca(pip)(H2O)3(Cl)].2H2O, [Zn(pip)(H2O)3(Cl)].4H2O, [Fe(pip)(H2O)2(Cl)2].6H2O, (where pip = deprotonated pipemidic), were synthesized through chemical reactions MgCl2.6H2O, CaCl2.2H2O, ZnCl2, FeCl3.6H2O metal salt chlorides with pipH chemother...