Sporotrichosis is a subacute or chronic granulomatous mycosis caused by fungus of the Sporothrix schenckii complex. It is considered to be a rare condition in most parts of the world. It mostly causes cutaneous infection but can also cause multisystemic disease. Unlike most deep cutaneous mycoses which have a primary pulmonary focus, it is usually caused by direct inoculation of the fungus into...

Acute generalized exanthematous pustulosis (AGEP) is characterized by acute onset of fever with a generalized erythematous pustular eruption. It seems that more than 90% of cases with AGEP are drug-induced [1]. The most frequently involved drugs are aminopenicillins, macrolides, antimycotic drugs, calcium channel blockers, carbamazepine, and paracetamol. We report a severe case of topical drug–...

INTRODUCTION Fluconazole is a widely used antifungal agent with a possible side effect of fixed drug eruption. However, this adverse drug effect is absent from the reported list of possible side effects of fluconazole. We are presenting a rare case in our report. CASE PRESENTATION A 25-year-old Iranian woman developed fixed drug eruptions on different sites of her body after taking five doses...

3. Thirion L, Nikkels AF, Piérard GE. Etoricoxib-induced erythemamultiforme-like eruption. Dermatology. 2008;216:227--8. 4. Kreft B, Wohlrab J, Bramsiepe I, Eismann R, Winkler M, Marsch WC. Etoricoxib-induced toxic epidermal necrolysis: successful treatment with infliximab. J Dermatol. 2010;37:904--6. 5. Augustine M, Sharma P, Stephen J, Jayaseelan E. Fixed drug eruption and generalised erythem...

Cetuximab is a recombinant human/mouse chimeric monoclonal antibody that targets the extracellular domain of the epidermal growth factor receptor (EGFR). Cetuximab is approved by the US Food and Drug Administration for the treatment of EGFR-expressing metastatic colorectal cancer as monotherapy in patients who are intolerant to irinotecan-based chemotherapy, or in combination with irinotecan in...

3. Thirion L, Nikkels AF, Piérard GE. Etoricoxib-induced erythemamultiforme-like eruption. Dermatology. 2008;216:227--8. 4. Kreft B, Wohlrab J, Bramsiepe I, Eismann R, Winkler M, Marsch WC. Etoricoxib-induced toxic epidermal necrolysis: successful treatment with infliximab. J Dermatol. 2010;37:904--6. 5. Augustine M, Sharma P, Stephen J, Jayaseelan E. Fixed drug eruption and generalised erythem...

Report of a Case A white male patient in his 60s developed pruritic and painful plaques over his upper body. His medical history included Wegner granulomatosis, which was successfully treated with cyclophosphamide in 2006. He took no medications daily and denied any drug allergies. A drug-related cutaneous eruption was considered at the initial evaluation, and sequential courses of corticostero...

Acute generalised exanthematous pustulosis (AGEP) is a rare cutaneous eruption, most often caused by commonly used antibiotics. It is characterised by an acute onset of non-follicular sterile pustular rash and erythema within hours or days of drug exposure and usually resolves spontaneously within 1-2 weeks once the drug is discontinued. Haemodynamic involvement in the form of shock is rare. He...