background: adverse cutaneous drug reactions (acdrs) are the most commonly reported adverse drug events. the causative drugs and clinical patterns of acdrs are different in various populations. this study was conducted to identify the clinical patterns, causative drugs and reasons for drug administration in patients hospitalized due to acdr. materials and methods: this retrospective study was c...

INTRODUCTION According to studies conducted in outpatients, it is estimated that 2.5% of children who are treated with a drug will experience a cutaneous adverse drug reaction (CADR). AIM To analyze the CADR reports involving pediatric patients recorded by three different university hospitals for describing common, serious, and interesting cutaneous drug eruption patterns. MATERIAL AND METH...

BACKGROUND Piroxicam is a widely used anti-inflammatory drug. Most adverse reactions affect gastrointestinal system, liver and skin. Fixed drug eruption although very unusual, has also been described, but with cutaneous involvement exclusively. We present the case of a 49-year-old man who suffered three episodes of fixed drug eruption with cutaneous-mucosal involvement, even simulating an autoi...

OBJECTIVE Cutaneous reactions are among the most common adverse reactions to drugs. The purpose of this study is to examine the aetiology and outcome of cutaneous drug reactions among patients admitted to the Dermatology Ward at the University Hospital of the West Indies. SUBJECTS AND METHODS This was a retrospective study looking at all patients who were admitted with a diagnosis of a cutane...

Fixed drug eruption (FDE) is a distinctive type of cutaneous drug reaction that characteristically recurs in the same locations upon re exposure to the offending drug. It is responsible for about 10% of all adverse drug reactions. Medications inducing fixed drug eruptions are usually those taken intermittently. Common drugs causing fixed drug eruptions are fluconazole, ciprofloxacin, doxycyclin...

Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) is a cutaneous drug reaction characterized by erythema over the buttocks, thighs, groin, and flexural regions most commonly associated with the use of beta-lactam antibiotics. Although the exact pathophysiology of this disease remains unknown, it is theorized to be the result of a delayed hypersensitivity response presentin...

Background: Cutaneous drug reaction seems to be relatively common The aim of the study was to recognize offending drugs, evaluate patients' characteristics and educate the patients to avoid selfadministration and re-administration of drugs. Methods: We retrospectively and prospectively analyzed data from Sina hospital in Tabriz (2000-2005) to determine the number of hospitalizations and visits ...

Background: The wide and indiscriminate use of drugs has increased the incidence and the modes of presentation of cutaneous drug reaction. Adverse cutaneous drug reactions are common, comprehensive information about their incidence, severity and ultimate health effects are unavailable. Objective: To study and evaluate incidence of adverse cutaneous drug reaction (ACDR) at our tertiary care hosp...

Sir, Cutaneous drug reactions have a wide variety of clinical features. Lichenoid drug eruptions (LDE) are rare and it may be difficult to differentiate them from idiopathic lichen planus (1, 2). Gold, quinine, quinidine and penicillamine are well-known inducers of such eruptions (1, 2), but there are only a few reports of lichenoid eruption induced by 3-hydroxy-3-methyl-glutaryl coenzyme A (HM...