Non-enantioselective alcohol dehydrogenases (ADHs) are rarely found in the biocatalysis portfolio. Generally, highly enantioselective ADHs sought for. Using such for oxidation of racemic alcohols generally results a kinetic resolution starting material, which is unfavourable if ketone represents product interest. In current contribution we report ADH from Sphingobium yanoikuyae ( Sy ADH) as non...

The secondary hydroxyl group involved in the oxidation, and the cis-vicinal secondary hydroxyl group, must have a D configuration jvith respect to t,he primary alcohol group adjacent to the site of oxidation. This specific mode of otida,tion facilitated the synthesis of several new ketoses. In a series of papers, Hudson and Richtmyer and their a.ssociates described the microbiological synthesis...

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