despite the role of oral corticosteroids in management of sever asthma, use of these drugs needs careful awareness of its many side effects. there are controversies about the role of methotrexate in lowering the need for corticosteroides in these patients. in this study an attempt has been made to determine methotrexate effects in corticosteroid dependent asthma. six patients were entered in a ...

the gastric cancer in iran is the fourth in the general population. this study was designed to determine the five-year survival rate of gastric cancer patients, and to assess its associated factors. we analyzed the data using a time-dependent covariates model, and recommend it for analyses of similar data. 281 gastric cancer patients with adenocarcinomatous pathology who had been operated on at...

This study was aimed at determining the analgesic effects of vigabatrin (VGB, a newer antiepileptic drug) in the acute thermal pain model (hot-plate test) in mice. Linear regression analysis was used to evaluate a dose-response relationship between logarithms of VGB doses and their resultant maximum possible antinociceptive effects (MPAE) in the hot-plate test in mice. From the linear equation ...

this study investigates the effectiveness of the antinociceptive effects of diclofenac, an nsaid, on the nociceptive behavior of morphine-treated rats on formalin test.rats were treated with morphine-containing drinking water for twenty one days, which induced morphine dependence. the antinociceptive effects of 8, 16, and 32 mg/kg doses of diclofenac were then evaluated and compared with distil...

thioredoxins (trxs) are small ubiquitous oxidoreductase proteins with two redox-active cys residues in a conserved active site (wcg/ppc) that regulate numerous target proteins via thiol/disulfide exchanges in the cells of prokaryotes and eukaryotes. the isoforms ostrx23 with a typical active site (wcgpc) and ostrx20 with an atypical active site (wctpc) are two  trx h- type isoforms in rice that ...

We present a ballistic description of the formation and propagation of the working surface of a relativistic jet. Using simple laws of conservation of mass and linear momentum at the working surface, we obtain a full description of the working surface flow parametrised by the initial velocity and mass injection. This allows us to compute analytically the energy release at any time in the workin...

Abstract: In this paper, the robust asymptotic stability problem for a class of nominally stable uncertain singularly perturbed systems with multiple non-commensurate time delays is considered. A delay-dependent criterion is first proposed in this paper to guarantee robust asymptotic stability of the system under consideration. Based on this result, the range of allowable bounds of the perturba...

In this paper directionally contextual concepts of variational analysis, based on dual-~pace cou-siructions similar to those in [4, 5], are introduced and studied. As an illustration of their usefulnes~, necessary and ft!so sufficient optimality conditions in terms of directioual subdiffeJ • ent.ials are established , and it is shown that they can be effective in the situations where known opti...