Introduction: Several factors such as diseases, medications and humoral agents can delay or speed up wound healing process. Because of the limited information about the hormonal changes during wound healing, in this study the relationship between serum levels of growth hormone, insulin and cortisol and wound healing in normal and diabetic rats was evaluated. Methods: Male Wistar rats )weigh...

objective: oxidative stress plays an important role in the etiology of diabetic complications. diabetes impairs hippocampus neurogenesis, synaptic plasticity, and learning. the aim of this study was to investigate the effects of hydroalcoholic extract of nigella sativa seed on oxidative stress in stz-induced diabetic rats' hippocampus. materials and methods: diabetes induced by 60 mg/kg st...

teucrium polium can reduce serum glucose. there are few reports in the literature related to this subject and the resolution of this mechanism requires further experiments. the aim of the present study was to evaluate the effects of teucrium polium aerial parts extracts on oral glucose tolerance tests and pancreas histology in streptozocin-induced diabetic rats. in order to prepare the aqueous ...

Diabetes mellitus is accompanied with disturbances in learning, memory, and cognitive skills in the humans and experimental animals. Due to the anti-diabetic and antioxidant activity of pelargonidin (PG), this research study was conducted to evaluate the efficacy of chronic oral PG on alleviating learning and memory disturbance in streptozotocin-diabetic rats. Male Wistar rats were divided into...

Diabetes mellitus is accompanied with disturbances in learning, memory, and cognitive skills in the humans and experimental animals. Due to the anti-diabetic and antioxidant activity of pelargonidin (PG), this research study was conducted to evaluate the efficacy of chronic oral PG on alleviating learning and memory disturbance in streptozotocin-diabetic rats. Male Wistar rats were divided into...

objective:diabetes mellitus is a common metabolic disorder that is one of the important factors in the etiology of injuries oxidant know the purpose the aim of the present study, was the effect of swimming training with arbutin on total oxidant status (tos) and total antioxidant status(tas) the kidney tissue of alloxan-induced diabetic rats.methods: for this purpose, 42 male wistar rats with an...

In this investigation, diabetes was induced in adult male Sprague-Dawley rats by single intraperitoneal injection of streptozotocin (STZ) at 45 mg kg-1 of body weight. A group comprised of 8 diabetic rats was treated with metformin at 100 mg kg-1 of body weight for reducing the elevated blood glucose level. The results revealed that, in the untreated diabetic rats, the body and testicular weigh...

background: diabetes mellitus is the most common metabolic disorder with many complications such as neuropathic pain which relief from it is a dilemma. objectives: to investigate the effect of hydroethanolic extract of rubus fruticosus on neuropathic pain in diabetic rats. materials and methods: in this experimental case –control study, forty eight male wistar rats (250±20 g) were divided rando...

objective(s) the aim of this study was to evaluate the effects of regular exercise in preventing diabetes complication in the hippocampus of streptozotocin (stz)-induced diabetic rat. materials and methods a total of 48 male wistar rats were divided into four groups (control, control exercise, diabetic and diabetic exercise). diabetes was induced by injection of single dose of stz. exercise was...