thyroid cancer, the most common endocrine malignancy worldwide, originates from follicular epithelial cells. it is classified as a well-differentiated thyroid carcinoma (wdtc), which includes both follicular (ftc) and papillary types (ptc), poorly differentiated thyroid carcinomas (pdtc), anaplastic thyroid carcinoma (atc), and/or arising from para-follicular calcitonin producing cells involve m...

The spectrum of thyroid cancers ranges from one of the most indolent to one of the most aggressive solid tumors identified. Conventional therapies for thyroid cancers are based on the histologic type of thyroid cancers such as papillary or follicular thyroid cancer (differentiated thyroid cancer (DTC)), medullary thyroid cancer (MTC), or anaplastic thyroid cancer (ATC). While surgery is one of ...

Although the incidence of differentiated thyroid cancer (DTC) is high, mortality quite low. In low and intermediate risk DTCs, reoperations due to inadequate treatment can increase morbidity, mortality, costs in patients. our study, current articles published on this subject were reviewed evaluated. According results, DTCs. Therefore, even DTC cases, adequate surgeries such as total or near thy...

TSH-suppressive therapy (ST) is part of the treatment protocol for differentiated thyroid carcinoma (DTC). There is however little evidence of its clinical effectiveness. On the other side, ST is not free from side effects related to the subclinical hyperthyroidism status induced in patients for a long time period. Because of this, widespread use of ST in all patients has recently been question...

Four patients are described in whom a follicular carcinoma developed following thyroidectomy for a benign follicular neoplasm. It is possible that the initial thyroid neoplasm was a well- differentiated follicular carcinoma which was microscopically indistinguishable from a benign adenoma. Realizing this pathologic pitfall in thyroid diagnosis, the need for meticulous examination of the pa...

PURPOSE Genetic polymorphisms in genes encoding for enzymes involved in the biotransformation of carcinogens have been shown to be relevant as risk for cancer and may be of considerable importance from a public health point of view. Considering that N-acetyltransferase 2 (NAT2) polymorphisms modulate the response to ionizing radiation, the strongest risk factor recognized to cause differentiate...

introduction: differentiated thyroid cancer (dtc) is the most common endocrine malignancy. this malignancy generally has an excellent prognosis with more than 90% long term survival. consequently, life quality improvement is the first priority especially in the young dtc survivors. in classic management of a new dtc patient, each therapeutic modality can significantly induce morbidities. in the...

Sorafenib, a tyrosine kinase inhibitor, is approved for the treatment of advanced differentiated thyroid carcinoma (DTC). Resistance to sorafenib may appear under treatment and may be associated with increased aggressiveness of the neoplasia. The present study reports the case of a 65-year-old male who underwent total thyroidectomy for a follicular thyroid carcinoma, Hürthle cell variant, in Fe...

OBJECTIVES The rate and impact of thyroglossal duct remnant (TGDR) visualization in patients with hypothyroidism after total thyroidectomy for differentiated thyroid carcinoma (DTC) have not yet been fully determined. The aim of this study was to assess the rate of TGDR visualization in post total thyroidectomy whole body scan (WBS) for DTC and to evaluate its impact on the outcome of I-131 abl...