نتایج جستجو برای: differentiation therapy
تعداد نتایج: 864024 فیلتر نتایج به سال:
Spinal cord injury (SCI) is one of the devastating conditions leading to functional and neurological deficits following road traffic accidents. To date, there is no definite treatment for repairing damaged spinal cord tissue. In this regard, cell therapy opens a new window in front of scientists by using different cells such as mesenchymal stem cells, olfactory ensheathing cells, Schwann cells,...
Background and purpose: Follicular fluid (FF) is a rich source of compounds for the development of oocyte. Wharton's jelly mesenchymal stem cells (WJ-MSCs) have a same differentiation origin with primordial germ cells, therefore, WJ-MSCs could differentiate into oocyte-like cells (OLCs) in the presence of appropriate factors. The purpose of present study was to isolate WJ-MSCs and then investig...
PURPOSE Stem-like tumor cells comprise a highly tumorigenic and therapy-resistant tumor subpopulation, which is believed to substantially influence tumor initiation and therapy resistance in glioma. Currently, therapeutic, drug-induced differentiation is considered as a promising approach to eradicate this tumor-driving cell population; retinoic acid is well known as a potent modulator of diffe...
Cancer is a progressive process characterized by uncontrolled cell proliferation and de-differentiation and clinical protocols involving cytotoxic agents remain a mainstay of conventional cancer therapies despite many non-specific adverse side effects. An alternative approach to potentially reduce the toxicity of anti-cancer therapy employs the induction of cancer cells to undergo terminal diff...
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