A 50-year-old university professor originally from South America had a 3-day history of paroxysmal attacks of rapid palpitations accompanied by near syncope and followed by transient flushing of her head and neck. She had a history of rheumatic mitral valve stenosis due to rheumatic fever at age 15, for which successful mitral commissurotomy was performed at age 36. Subsequently, recurrent atta...

This study was designed to evaluate further the antagonism between digitalis and potassium. Potassium was given by intravenous infusion to six dogs (1) before digitalization, (2) after injection of "therapeutic" doses of digitoxin, and finally (3) after injection of "toxic" doses of the drug. P OTASSIUM is used in the treatment of cardiac arrhythmias thought to be due to toxic effects of digita...

We wanted to know if incubation time and temperature for many radioimmunoassay methods could be standardized, to decrease assay time and so improve efficiency. Percentage binding was determined for triiodothyronine, thyroxine, digoxin, digitoxin, testosterone, aldosterone, estradiol, and diphenylhydantoin when the reaction mixtures were incubated at 6-8, 22, or 37 degrees C for various periods ...