نتایج جستجو برای: early onset breast cancer
تعداد نتایج: 1725716 فیلتر نتایج به سال:
Background and purpose: Breast cancer is one of the most common malignancies in women and early diagnosis of this cancer is a key element for successful treatment. Breast cancer is a multistep disease in which a virus can play a role. Epstein-Barr Virus (EBV) is identified as an important factor in human cancer. This study investigated the relationship between EBV and breast cancer. Materials ...
Germline mutations in the human breast cancer genes BRCA1 and BRCA2 account for a substantial proportion of familial, early-onset breast and ovarian cancers. The present study reports a novel disease-causing BRCA1 mutation, nucleotide 3020insCT/c.2901insCT, in a 55-year-old Spanish female with breast and ovarian cancer. This frameshift mutation creates a premature stop codon at amino acid 1000,...
background and objective: neonatal sepsis is defined as presence of clinical signs accompanied by positive blood culture in newborns less than one month of age. sepsis is a common cause of hospital admission in neonates, and it is known as one of the main causes of mortality among them, not only in developed countries but in developing ones. delay in diagnosis and appropriate antibiotic therapy...
bilateral synchronous male breast cancer is very rare. a 63-year-old male presented with rapidly progressive enlarging bilateral breast masses without ulceration and bloody nipple discharge. synchronous bilateral breast cancer was diagnosed by fine needle aspiration cytology. pathology study revealed grade 2 invasive ductal carcinoma in both breasts. he underwent a bilateral modified radical ma...
BACKGROUND Moderate-risk genes have not been extensively studied, and missense substitutions in them are generally returned to patients as variants of uncertain significance lacking clearly defined risk estimates. The fraction of early-onset breast cancer cases carrying moderate-risk genotypes and quantitative methods for flagging variants for further analysis have not been established. METHO...
BACKGROUND The aim of this study was to identify BRCA1 and BRCA2 mutations in the Estonian population. We analyzed genetic data and questionnaire from 64 early-onset (< 45 y) breast cancer patients, 47 familial cases (patients with breast or ovarian cancer and a case of these cancers in the family), and 33 predictive cases (patients without breast or ovarian cancer, with a family history of suc...
BRCA1 (breast cancer early-onset 1) alternative splicing levels are regulated in a cell-cycle- and cell-type-specific manner, with splice variants being present in different proportions in tumour cell lines as well as in normal mammary epithelial cells. The importance of this difference in the pathogenesis of breast cancer has yet to be determined. Developing an understanding of the impact of B...
introduction: many training programs have been conducted, aiming to encourage women to perform breast self-examination for early detection of breast cancer. this study aimed to review studies performed on efficacy of educational interventions to correct women’s behavior in breast self-examination. method : through systematic search of medline and isi web of science databanks to retrieve title...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید