The role of the Notch ligand Jagged1 in hepatic fibrosis remains to be elucidated. In the current study, we investigated the role of Jagged1 in the activation of hepatic stellate cells (HSCs) and development of hepatic fibrosis in rats. In vitro, Jagged1 in HSCs was downregulated and upregulated by Jagged1 siRNA and pcDNA3.1 Jagged1, respectively. The levels of epithelial-mesenchymal transition...

Purpose This study aims to present a twofold machine learning (ML) model, namely, EDU-AI, and its implementation in educational buildings. The specific focus is on classroom layout design, which investigated regarding of ML the early phases design. Design/methodology/approach introduces framework adopts generative adversarial networks (GAN) architecture Pix2Pix method. processes data collection...

The article discusses the capabilities of Minecraft: Education Edition (Minecraft EDU) platform, built on ideas gamification, to motivate schoolchildren study informatics. It describes how work with platform (creating an account, importing worlds, creating programs); basic concepts associated platform; approximate planning lessons thematic section "Algorithmics" for sixth grade; general idea in...

Edu Smart is a learning management system software (LMS) that was built as one of the distance solutions during COVID-19 pandemic and became resource for activities administration activities. This research aims to measure quality LMS related operational products used by McCall method. The analysis carried out on aspects product operation consisting factors correctness, reliability, efficiency, ...

This article presents an autoethnographical account of my foray into Spanish immersion education in Costa Rica as a professor of multilingual education at a university in Canada. This language-learning journey was inspired by curiosity about the growing trend for Internet marketing of second-language learning as a form of tourism, which I label edu-tourism. I map the course of my edu-tourism ex...

This paper presents the results of an exploratory study examining bachelor degree students’ experiences of learning with a new generation learning management system Edu 2.0 combined with Web 2.0 applications. The authors discuss students’ perceptions of formal and informal activities within this environment as captured through a collection of surveys, activities’ tracking, and assessment. The m...

Here we report one new case each of an X-autosome translocation (maternally derived), and an X-Y-chromosome translocation. Besides characterizing the involved breakpoints and/or imbalances in detail by molecular cyto-genetics, also skewed X-chromosome inactivation was determined on single cell level using 5-ethynyl-2-deoxyuridine (EdU). Thus, we confirmed that the recently suggested EdU approac...

ALFRED (the ALelle FREquency Database) is designed to store and disseminate frequencies of alleles at human polymorphic sites for multiple populations, primarily for the population genetics and molecular anthropology communities. Currently ALFRED has information on over 180 polymorphic sites for more than 70 populations. Since our initial release of the database we have focussed on increasing t...

The process of ethylene production from ethane dehydrogenation is one of the interesting processes in the field of conversion the petroleum light gases to the valuable products. In this process, the outlet gaseous product is a combination of ethylene, ethane and hydrogen. Effective separation techniques are required for separation of ethylene from unreacted ethane. Here a new adsorbent approach...