نتایج جستجو برای: experimental autoimmue encephalomyelitis model

تعداد نتایج: 2637440  

Journal: :Journal of clinical microbiology 2007
Kenitiro Ito Mariko Iida Mitsugu Yamazaki Kazuo Moriya Sanae Moroishi Jun Yatsuyanagi Takayuki Kurazono Noriaki Hiruta Orn-Anong Ratchtrachenchai

We developed a quick genetic approach to screen variants of the intimin gene (eae) by using a heteroduplex mobility assay (HMA) that targets the 5' conserved region of eae. The eae variants were categorized into 4 major HMA types and 10 minor subtypes.

Journal: :Current Protocols in Neuroscience 2001

Journal: :modares journal of medical sciences: pathobiology 2012
forouzan yousefi masoumeh ebtekar masoud soleimani seyed mahmoud hashemi

objective: this study investigated the effects of adipose-derived mesenchymal stem cells (mscs) and conditioned medium injection on cell infiltration in the brains of an experimental c57bl/6 mice model of autoimmune encephalomyelitis (eae). methods: eae was induced with myelin oligodendrocyte glycoprotein (35-55 peptides) in 20 mice. mscs were obtained from the adipose tissue of c57bl/6 mice a...

Journal: :Brain : a journal of neurology 2014
Sarah Al-Izki Gareth Pryce Deborah J R Hankey Katie Lidster Stephanie M von Kutzleben Lorcan Browne Lisa Clutterbuck Cristina Posada A W Edith Chan Sandra Amor Victoria Perkins Wouter H Gerritsen Kim Ummenthum Regina Peferoen-Baert Paul van der Valk Alexander Montoya Simon P Joel John Garthwaite Gavin Giovannoni David L Selwood David Baker

Progressive multiple sclerosis is associated with metabolic failure of the axon and excitotoxicity that leads to chronic neurodegeneration. Global sodium-channel blockade causes side effects that can limit its use for neuroprotection in multiple sclerosis. Through selective targeting of drugs to lesions we aimed to improve the potential therapeutic window for treatment. This was assessed in the...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت مدرس - پژوهشکده مهندسی فرایند 1395

abstract: mineral scaling in oil and gas production equipment is one of the most important problem that occurs while water injection and it has been recognized to be a major operational problem. the incompatibility between injected and formation waters may result in inorganic scale precipitation in the equipment and reservoir and then reduction of oil production rate and water injection rate. ...

Journal: :Applied microbiology 1971
H J Hearn H R Tribble S C Nagle O C Bowersox

An attempt was made to identify nutritional additives that influence the replication of Venezuelan equine encephalomyelitis virus in suspension cultures grown in a defined serum-free medium. Proline, serine, and choline enhanced titers of the virulent PES strain; the progeny population, however, possessed a virulence character that was somewhat different from that of the PES inocula. These nutr...

Mahdieh Keradi, Maryam Soleimani Masoumeh Masoumipoor Mehdi Mehdizadeh, Seyed Behnamedin Jameie, Soraya Mehrabi

Objective(s): Multiple Sclerosis (MS) is known as a progressive inflammatory CNS disease. Cytokines belong to Th1 or Th2 family and inflammatory cells, play significant role in pathophysiology of MS. Thus, any treatment supposed to influence the relation between Th1 to Th2 cytokines expression. Although vitamin D has been prescribed as a therapeutic supplement of MS for a long time, it is not c...

Journal: :The Journal of Experimental Medicine 1938
Peter K. Olitsky Carl G. Harford

Minute amounts of antiserum injected intraperitoneally protect against large doses of equine encephalomyelitis virus given intramuscularly or intraperitoneally in 12 to 15 day old mice. Antiserum given intraperitoneally with virus intracerebrally or intranasally results in little or no protection. These phenomena occur as well when serum-virus mixtures are injected at the different sites. The m...

Journal: :The Journal of Experimental Medicine 1941
Isabel M. Morgan

The experiments described in this paper were carried out with the Rockefeller Institute strain of albino mice and with the Eastern strain of the virus of equine encephalomyelitis. 1. The observation was confirmed that with increasing age of mice there occurred a decrease in susceptibility to intraperitoneal injection of active virus; also, the length of incubation period of those which succumbe...

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