We present a new simple model for the evolution of premating reproductive isolation. Using this model we first analyze the level of genetic variability maintained by mutation in a large stable population. Then we consider the plausibility of the evolution of strong premating reproductive isolation after a founder event. We demonstrate that after a founder event a new adaptive combination of gen...

Gastroenterology in India started developing as a specialty in the sixties. The Indian Society of Gastroenterology (ISG) was formed in 1960 with Maj.Gen.Amir Chand as the Founder-President and Dr. H K Chuttani as the Founder-Secretary. This was just two years after the foundation of OMGE, the World Gastroenterology Organization, on May 29, 1958, the last day of the first World Congress of Gastr...

When evaluating patients for possible deleterious BRCA mutations, determining ancestry may be a critical issue. Founder mutations are present in ethnically isolated populations and are responsible for a significant proportion of breast and ovarian cancer cases attributed to an inherited susceptibility. Founder mutations have been identified in Ashkenazi Jews,[1-3] French Canadians,[4] Japanese,...

In this study, the karyometry of different Triatoma infestans populations from different states of Brazil was analyzed and compared with those of a population from Cochabamba. No significant differences were found between the population from Cochabamba and those from Brazil. These results are consistent with the origin of the T. infestans populations of Brazil by a founder effect from Cochabamb...

  The Akhal-Teke is an ancient horse originat-ing from Asia where it was used by nomadic tribes and used as a warhorse. Lameness examinations require proper interpretation of clinical and radiographic findings. Therefore, understanding of normal radiographic findings of the foot is necessary. Although the radiographic appearance of the normal foot must be understood to recognize abnormalities ...

Human genetic and phenotypic diversity declines with distance from Africa, as predicted by a serial founder effect in which successive population bottlenecks during range expansion progressively reduce diversity, underpinning support for an African origin of modern humans. Recent work suggests that a similar founder effect may operate on human culture and language. Here I show that the number o...

The extent to which random processes such as founder events contribute to evolutionary divergence is a long-standing controversy in evolutionary biology. To determine the respective contributions of founder effects and natural selection, we conducted an experiment in which brown anole (Anolis sagrei) lizard populations were established on seven small islands in the Bahamas, from male-female pai...

Somatic mtDNA mutations and deletions in particular are known to clonally expand within cells, eventually reaching detrimental intracellular concentrations. The possibility that clonal expansion is a slow process taking a lifetime had prompted an idea that founder mutations of mutant clones that cause mitochondrial dysfunction in the aged tissue might have originated early in life. If, converse...

Crowdfunding platforms offer promising opportunities for project founders to publish their project ideas and to collect money in order to be able to realize them. Consequently, the question of what influences the successful funding of projects, i.e., reaching the target amount of money, is very important. Building upon media richness theory and the concept of reciprocity, we extend previous res...

We investigate how potential co-founders' perceptions of a founder's obsessive passion (OP) influence the decision to join venture team. Using conjoint experiment with primary sample 116 founder-entrepreneurs and validating it an additional 59 founder entrepreneurs, we found that co-founders were more likely if they perceived had OP for developing ventures. Potential less founding Further, sign...