This paper aims to investigate the mechanical properties of specimens printed by 3D open-source printers. It discusses effect five factors (part orientation, layer height, extrusion width, nozzle diameter, and filament temperature) on ultimate tensile strength impact toughness 3D-printed samples. A 25–1 resolution V fractional factorial experiment was run with 16 samples a Prusa I3 MK3S in PLA....

Generalized linear models (GLMs) have been used widely for modelling the mean response both for discrete and continuous random variables with an emphasis on categorical response. Recently Yang, Mandal and Majumdar (2013) considered full factorial and fractional factorial locally D-optimal designs for binary response and two-level experimental factors. In this paper, we extend their results to a...

This paper simplifies a previous exposition of Rao’s 1947 proof of his inequalities for orthogonal arrays. A key issue in the proof is the way in which one defines effects in a fractional factorial design. Here we replace the definition used in the earlier exposition with a simpler one, based on a more obvious interpretation of what Rao wrote and more in line with common practice, and show that...

Fractional factorial split-plot designs are widely used when it is impractical to perform fractional experiments in a completely random order. When there too many subplots per whole plot, or few plots, with replicated settings of the plot factors preferred. However, such an important study undeveloped literature. This paper considers WP from viewpoint clear effects. We investigate sufficient an...

When several treatments are available for evaluation in a clinical trial, different design options are available. We compare multi-arm multi-stage with factorial designs, and in particular, we will consider a 2 × 2 factorial design, where groups of patients will either take treatments A, B, both or neither. We investigate the performance and characteristics of both types of designs under differ...

The aim of this study is to prepare fluvastatin nanostructured lipid carriers (FLV-NLCs) in order to find an innovative way to alleviate FLV-associated disadvantages. The limitations include poor solubility and extensive first-pass metabolism, resulting in low (30%) bioavailability and short elimination half-life (1-3 hours). FLV-NLCs were prepared by hot emulsification-ultrasonication method. ...

We demonstrate how to use SAS to design experiments for multicomponent interventions for multifactorial health syndromes. Multifactorial syndromes are health conditions that have more than one risk factor related to the outcome and require interventions with several components that target different risk factors. The design and analysis of multicomponent trials are complicated by the number of f...