objective her-2/neu gene is overexpressed in diverse human cancers and studies suggest a role of its product – p185 protein – in tumor progression by specifically promoting the invasive capacity of tumor cells. our aim was to evaluate her-2/neu content in resectable gastric cancer in this geographical region and assess the relationship between p185 expression and clinicopathologic tumor paramet...

gastric cancer is the most common gi cancer. it has a very high incidence rate in the northeastern iran.contrary to western countries and japan, the incidence of gastric cancer has been increasing in iran during the past two decades. helicobacter pylori infection is the most important risk factor for developing gastric cancer. however, the presence and influence of other environmental and genet...

background: opioid peptides and their receptors are present in the majority of body tissues including gastrointestinal tract.  heroin is one of the opioid derivatives that abuse increasingly today.  so far, there is no study on the effect of acute heroin administration on gastric acid and pepsin secretion.   objective:  to define the effect of the acute heroin consumption on basal and vagal-sti...

background: gastric and colorectal adenocarcinoma are the second and the fifth most common cancers in iran, respectively. expression of cytokeratin 7 (ck7) is established in most malignancies including gastric and colorectal adenocarcinoma. demonstration of ck7 could be related to prognostic factors and help to the better management of the patients. the objective of our study was to evaluate th...

peptic ulcer is a very common disorder in horse race and foals. in the present research possible relationship between gastric ulcer and the prevalence of cardiac arrhythmia were studied in two different horse race. in this respect, 13 caspian miniature horses and 8 arab horses were studied. gastric ulcers and cardiac arrhythmias were diagnosed in 13 horses (62%) and 12 (57%) out of 211 horses, ...

background: saffron is the dried stigmata of the flowers of saffron (crocus sativus l., iridaceae). saffron is well known for the treatment of gastric disorders in traditional medicine.   objectives: in the search for new potential antiulcer agents, the effects of the ethanol extract of saffron and its active constituents crocin and safranal as compared with omeprazole against gastric ulcer ind...

absractgastritis cystic polyposa is a rare and peculiar polypoid lesion arising at a gastroenterostomysite, and almost always on the gastric side. it is characterized by elongationof the gastric foveolae along with hyperplasia and cystic dilatation of the gastricglands extending into the submucosal layer. esophagogastroduodenoscopy in a47-year-old woman without any history of gastric operation ...

abstract background: gastric cancer is one of the most common cancers in the world especially in iran. there are many genomic and molecular factors that cause gastric cancer to occur. also, many markers that associate with tumor invasiveness have been known.  e-cadherin is a calcium- mediated cell adhesion molecule. in some studies, abnormal expression of e-cadherin has been seen in gastric car...