Falcaria vulgaris is a member of Umbelliferae family and is used for treatment of stomach disorders in the folk medicines of the west of Iran. This study was designed to evaluate the gastroprotective effect of F. vulgaris extract on ethanol (50%) induced gastric ulcers in rat. Thirty five young white male rats were divided to five groups (7 rats/ group).Three case groups received plant extract ...

Deregulation in prostaglandin (PG) biosynthesis, oxidative stress, inflammation, and apoptosis play a major role in the pathogenesis of nonsteroidal anti-inflammatory drug (NSAID)-induced gastropathology. Although the underlying molecular mechanisms involved in this pathophysiological condition is not fully understood, considerable progress has been made in recent years. Also, substantial progr...

BACKGROUND Zingiber zerumbet Smith is a perennial herb, broadly distributed in many tropical areas. In Malaysia, it's locally known among the Malay people as "lempoyang" and its rhizomes, particularly, is widely used in traditional medicine for the treatment of peptic ulcer disease beyond other gastric disorders. AIM OF THE STUDY The aim of the current study is to evaluate the gastroprotectiv...

PURPOSE The cation exchanger, a potentiated clinoptilolite (Absorbatox™ 2.4D), is a synthetically enhanced aluminosilicate. The aim of this study was to evaluate the possible benefits of a potentiated clinoptilolite as a gastroprotective agent in reducing the severity of clinical symptoms and signs associated with 1) endoscopically negative gastroesophageal reflux disease (ENGORD) and 2) nonste...

Minocycline (MCN), a semi-synthetic tetracycline derivative possesses pleiotropic effects and provides protection against a number of disease models. However its effect on gastric ulcers has not been studied. The present investigation was undertaken, to study the gastro-protective potential of MCN in experimentally induced gastric ulcers in rats. MCN (10, 30, 100 mg/Kg) was tested for gastric s...