Objective: Atherosclerosis of coronary arteries is the most significant cause of disability and mortality worldwide and the most efficient physiological process reducing the risk of this disease is RCT. ABCG8 plays a crucial role in the reverse transfer of cholesterol from macrophages to the liver. The aim of this study is to study the effect of eight weeks aerobic exercise on the atherogenic r...

Myogenin gene (MYoG) affects the synthesis of muscle myofibrillar growth and increase of meat production. The myostatin (MSTN) gene is identified as a specific negative regulator of skeletal muscle growth. Reduction of the expression level of MSTN throughmutation in the sequence of this gene leads to an increase of myogenesis and regeneration of muscle cells during the postnatal growing period ...

Abstract Background and Aims: The number of new cancer cases with considerable mortality is increasing worldwide. Since the inability of current therapies in treatment of patients and prevention the progress of tumors with fewer side effects, implementation of new methods is needed. Gene therapy has widespread systemic cytotoxic effects against tumor cells. Rotavirus NSP4 has been shown to...

Background: The key enzyme of estrogen biosynthesis, aromatase cytochrome P450,is encoded by the CYP19 gene.CYP19 plays an important role in the development,function,an regulation of the female reproduction cycle. Thus, it is the potential candidate gene affecting fertility performance in human. CYP19 transcripts are expressed mainly in the ovary,testes,breast,adipose tissue and brain. Tissue e...

the fecundity in sheep has been much interested for producers due to its economical importance. growth differentiation factor 9 (gdf9) is an autosomal gene with over dominance effect for twosingle nucleotide polymorphisms(snps), which resulted in sterility in homozygote mutant ewes and additive effect for three snps, without showing sterility event. in the present study, dna was extracted from ...

Eggshell quality is the main trait to assess egg quality. Marker assisted selection can be used to improve this trait. During eggshell formation, a mass of inorganic minerals is deposited. The Sodium Channel (SCNN1) gene family plays an essential role in cation transportation and SCNN1g is a member of this gene family. The objective of this study was to estimate the frequency of SCNN1g gene var...