asthma is a disorder of increasing severity and prevalence. recent knowledge about the pathogenesis of asthma emphasizes its inflammatory nature. cpg oligonucleotides are a class of compounds containing motifs based on the cytosine-guanine dinucleotides (cpg-odns). these motifs are suppressed in mammalian dna. they induce inflammation in mammals characterized by the induction of t helper type 1...

Large protein-sized synthetic supramolecular architecture is rare and certainly has not yet achieved the structural and functional complexity of biomolecules. As multiple, identical copies of a few building blocks are repetitively used, a highly symmetrical architecture results with limitations in function. In marked contrast, functional structures in nature are often assembled with high geomet...

according to the forms of sassanian medallions designed on the textures sassanid, it’s very impressive in the distinctive features, the variety of design and style of drawing. sassanid era peak of excellence in the art of silk fabrics and textiles, especially the development of their industry. but it should also be stated, that one of the important reasons for the existence of exquisite designs...

The present paper deals with the mosaic pavements that embellished public buildings, semi-public and private houses between 80s of 4th c. first two decades 5th in most important cities late antique province Thrace - Philippopolis Augusta Traiana are unearthed so far. This was a period great significance for development both which though developed different way until time, were now united use fu...

The Nucleic Acid Database (NDB) (http://ndbserver.rutgers.edu) is a web portal providing access to information about 3D nucleic acid structures and their complexes. In addition to primary data, the NDB contains derived geometric data, classifications of structures and motifs, standards for describing nucleic acid features, as well as tools and software for the analysis of nucleic acids. A varie...

The Mouse Brain Web, a federated database, provides for the construction of anatomically correct models of mouse brain networks. Each web page in this database provides the position, orientation, morphology, and putative synapses for each biologically observed neuron. The Mouse Brain Web has been designed to support (1) mapping of the spatial distribution and morphology of neurons by type; (2) ...

We present solution-state NMR structures for two putative venom peptides from Sicarius dolichocephalus. These peptides were identified from cDNA libraries created from venom gland mRNA and then recombinantly expressed. They are the first structures from any species of Sicarius spiders, and the first peptide structures for any haplogyne spiders. These peptides are homologous to one another, and ...

To examine the effect of concurrent verbal encouragement on the performance of the WAnT in female athletes vs. female non-athletes. College-age female subjects were recruited where ten of the subjects were intercollegiate athletes (ATH, n1 =10) and the nine were non-athletes (NON, n2 =9). The WAnT was novel to all subjects and the subjects were blinded to the study's purpose. Prior to the exper...

The tmRNA-SmpB system releases ribosomes stalled on truncated mRNAs and tags the nascent polypeptides to target them for proteolysis. In many species, mutations that disrupt tmRNA activity cause defects in growth or development. In Caulobacter crescentus cells lacking tmRNA activity there is a delay in the initiation of DNA replication, which disrupts the cell cycle. To understand the molecular...