Excessive exposure to alcohol prenatally has a myriad of detrimental effects on the health and well-being of the offspring. It is unknown whether chronic low-moderate exposure of alcohol prenatally has similar and lasting effects on the adult offspring's health. Using our recently developed Sprague-Dawley rat model of 6% chronic prenatal ethanol exposure, this study aimed to determine if this m...

AIMS To examine the association between sleep disturbances during pregnancy and risk of gestational diabetes mellitus. METHODS From 2010 to 2012, 12 506 women in Tianjin, China, were screened using a 50-g 1-h glucose challenge test at 24-28 weeks' gestation. Those with glucose challenge test values of ≥ 7.8 mmol/l were invited to further undergo a 75-g 2-h oral glucose tolerance test. Gestati...

Objective: Gestational diabetes mellitus (GDM) is the most common endocrine disorder in pregnancy and number of pregnant women resistant to oral glucose tolerance test (OGTT) has increased significantly recent years. In this study, we investigated extent resistance OGTT screening followed-up our hospital effect situation on newborn.
 Material Method: Pregnant their babies who were followed...

The aim of this study was to describe the dietary patterns of pregnant women in northern Puerto Rico and explore associations between diet factors with pregnancy related measurements. This analysis is based on the Puerto Rico Testsite for Exploring Contamination Threats (PROTECT), a prospective cohort that is studying environmental risk factors for preterm births in PR. Participants completed a...

Two experiments were conducted to determine the effect of nonwaxy (amylose and amylopectin starch) or waxy (amylopectin starch) sorghum on growth, carcass traits, and glucose and insulin kinetics of pigs. In Exp. 1 (95-d), 60 crossbred barrows or gilts (initial and final BW of 24 and 104 kg) were allotted to three treatments with five replications of four pigs per replicate pen in a randomized ...

Acute and sustained soluble dietary fibre (SDF) consumption are both associated with improved glucose tolerance in humans and animal models (e.g. porcine). However, the effects on glucose tolerance in grower pigs, adapted to diets with a combination of SDF have not been studied previously. In this experiment, cereal SDF wheat arabinoxylan (AX) and oat β-glucan (BG) were fed individually and in ...

AIM Inhibition of sodium/glucose cotransporter 2 (SGLT2), the key transport protein in renal glucose reabsorption, promotes glucose excretion and represents a new concept in the therapy of type-2 diabetes. In addition, SGLT2 inhibition elevates circulating glucagon concentrations and enhances hepatic glucose production. Since SGLT2 is expressed in human pancreatic α-cells and regulates glucagon...