A 37-year-old male case was admitted with goiter. Ultrasonography of thyroid showed a 5 cm cystic nodule in the left lobe with a 1.5 cm solid component. Fine needle aspiration biopsy revealed atypia of undetermined significance or follicular lesion. The patient was operated on. The pathological diagnosis was reported as papillary thyroid carcinoma. The immunohistochemical examination showed mul...

BACKGROUND Various therapeutic options are available for the management of Langerhans cell histiocytosis. However, treatment administered to control this disease may be complicated by acute leukemia. CASE PRESENTATION A 34 years old male was diagnosed to have Langerhans cell histiocytosis in March 1999. Unfortunately, the cytotoxic chemotherapy and radiotherapy given to control the repeated r...

UNLABELLED INTRODUCTION Langerhans cell histiocytosis is a rare disease within the adult population, with very few cases reported as solitary hypophyseal lesions in adults. Of the reported cases, most have been treated successfully with surgery, radiotherapy, and/or chemotherapy. Radiotherapy has been thought to be curative at the relatively low dose of 20Gy. Here we report a case of recurre...

INTRODUCTION Adult pulmonary Langerhans'cell histiocytosis, also referred to as histiocytosis X, is a disorder of unknown etiology which affects preferentially young smokers. The disease is characterized by granulomatous lesions which progressively invade and destroy distal airways, leading to the formation of characteristic cicatricial kystic lesions. Florid granulomas contain numerous Langerh...

INTRODUCTION Sinus histiocytosis with massive lymphadenopathy, also known as Rosai-Dorfman Syndrome, a nonmalignant variant of histiocytosis (1) is a chronic reactive disorder. It presents as a benign, chronic, massive enlargement of cervical lymph nodes (LN) accompanied by fever, leukocytosis, elevated erythrocyte sedimentation rate (ESR) and hyperglobulinamia (2). There is no malignant prolif...

This paper describes the clinical investigation, and light and electron microscope findings in a Pakistani girl who developed bilateral orbital and eyelid swellings in association with lymphadenopathy. The findings do not correlate with any of the previously recognized causes of these symptoms although similarities with some of the lymphoreticular disorders, in particular Hand-Schuller-Christia...

In this paper the authors reported 2 cases of Sinus Histiocy-tosis . The first , an 11 year s o1d gir1 with massive 1ymphadnopathy of 10 CM diameter and 3 months duration otherwise normal. Paraclinic exams wer normal including BM. Diagnosis was confirmed by cervical node biopsy. She was followed clinically and was cured in 8 months. The second case, a 6 years old boy with massive cervical lymph...

Introduction:Langerhans cell histiocytosis (LCH) refers to a group of rare reticuloendothelial system disorders and it occurs most often in young adults and children. A 57-year-old edentulous female patient who complained of dull pain in the posterior region of the mandible referred to the dental office, with a complaint of dull pain in the posterior region of the mandible. The lesion was diagn...

A case report of histiocytosis X in a 2 years old in­faut, primarily admitted a for jaundice is discussed. Major clinical manifestations included: Jaundice, bi­lateral otitis media. pallor and loss of weight. Clinical examination revealed hepatosplenomegaly. lymphadenopathies and sever anemia. Seborrr.eic eruptions and ptechias appeared over the scalp and other parts of body surface a few days ...