langerhans cell histiocytosis (lch) is a rare disorder described as three different entities including eosinophilic granulomaof bone, the hand-schuller-christian syndrome, and letterer-siwe disease. lch is currently classified into singlesystem lch, and multisystem lch. patients with single system lch have an excellent prognosis, and are mostlytreated with local therapy. multisystem lch is subd...

histiocytosis of langerhans cells (class 1 histiocytosis) consists of a range of clinical manifestations, including bone eosinophilic granuloma, hand-schüller-christian syndrome, and letterer-siwe disease. these syndromes represent a spectrum of severity and prognosis of an underlying disorder which is usually sporadic. this report describes three cases in one family, who developed the disease ...

Histiocytosis, according to Histiocyte Society2, is traditionally classifi ed into three main groups: Class I: (Langerhans cell histiocytosis), formerly called X histiocytosis Class II: Histiocytosis of other mononuclear phagocytes different from Langerhans cells Class III: Histiocytic malignancies.1,3,4 Nevertheless, Langerhans cell Histiocytosis is the currently preferred term. It is classifi...

indeterminate cell histiocytosis is a very rare disorder of histiocytes proliferation. it has both langerhans and non-langerhans cell histiocytosis immunophenotypic features. we described a 45-year-old man with a 2 years history of multiple yellow-brown papules and a few red nodules on his trunk and extremities. no internal involvement was detected first and after 8 months. as his lesions were ...

The histiocytoses are a group of proliferative disorders of themonocyte-macrophage lineage that are neoplastic or reactive innature. Based on immunophenotyping and electron microscopy,two main groups have been recognized namely 1) Langerhanscell histiocytosis (LCH) and 2) non- Langerhans cell histiocytosis(non-LCH). In this study, a fairly rare disease of the non-LCHgroup, generalized eruptive ...

CONTEXT Pulmonary Langerhans cell histiocytosis is the most common and best known pulmonary histiocytic lesion; however, the realm of pulmonary histiocytic lesions also includes an assortment of uncommon diseases that may exhibit pulmonary involvement. OBJECTIVE To review pulmonary Langerhans cell histiocytosis and other pulmonary histiocytoses to better ensure correct diagnosis and optimal a...

BACKGROUND Langerhans cell histiocytosis affects mainly young children and features an accumulation of CD1a+ dendritic Langerhans cells in the bone, skin, and other organs. A few cases of Langerhans cell histiocytosis on the penis have been reported in the literature. We present a case of Langerhans cell histiocytosis on the penis and review the similar cases in the literature. CASE PRESENTAT...

INTRODUCTION Langerhans cell histiocytosis (LCH) is a proliferative disorder of histiocytes in multiple organs. Langerhans cell histiocytosis involves bones, skin, lung and other organs. CASE PRESENTATION This study describes a seven-month-old Iranian girl who presented with skin rash and cervical lymphadenopathy. Langerhans cell histiocytosis was suspected when it was associated with anemia,...

STATEMENT OF THE PROBLEM Langerhans cell histiocytosis is a rare disease with unknown pathogenesis and is characterized by local or disseminated proliferation of Langerhans cells. There is no previous investigation on prevalence of oral Langerhans cell histiocytosis in Iranian population. PURPOSE The purpose of this study was to assess the relative frequency of oral Langerhans cell histiocyto...

conclusions pericardial effusion was a rare finding in this case of langerhans cell histiocytosis. pericardial effusion in langerhans cell histiocytosis, which is an unusual presentation, should be considered when the patient experiences respiratory distress. introduction langerhans cell histiocytosis (lch) is a proliferative disorder of histiocytes in multiple organs. langerhans cell histiocyt...