Histocompatibility and its current application in kidney transplantation are discussed. Both theoretic and clinical aspects of human leukocyte antigen testing are described, including antigen typing, antibody detection, and lymphocyte crossmatching. Living related, living unrelated, and cadaveric donor-recipient matching algorithms are discussed with regard to mandatory organ sharing and graft ...

Biopsies tumour cells from astrocytoma-bearing patients were grown in primary culture for 3-5 days. Both low and high grade tumours were represented in the study. The cultured cells could be shown to express the HLA-A and -B antigens using a multispecific allo-antiserum and a rabbit anti-beta-2 microglobulin antibody. The tumour cells were negative for the HLA-DR determinants when tested with e...