background the human leukocyte antigen (hla) system is widely used as a strategy in the search for the etiology of renal function impairment. objectives this study was carried out to detect the most common hla alleles’ distribution in kidney transplant in both donors and recipients, and clarify the association between hla alleles and renal dysfunction immediately after transplantation. patients...

Non-identical transplants (allogeneic) have been a modern medicine milestone; however, the major pitfall for completed succeed is recognition of foreign organ by immune system. The myriad variations in sequence molecules histocompatibility complex (MHC) or human leukocyte antigen (HLA) between individuals are cause allograft rejection. Thus, B T lymphocytes receptor occurs hypervariable regions...

Multicellular tissue compatibility, or histocompatibility, restricts fusion to close kin. Histocompatibility depends on hypervariable cue genes, which often have more than 100 alleles in a population. To explain the evolution of histocompatibility, I here take a historical approach. I focus on the specific example of marine invertebrate histocompatibility. I use simple game-theoretical models t...

A common skin disorder called psoriasis causes thickened patches of the skin. Typically, it is discovered to be covered with silvery scales. Although regarded as a condition, actually outcome an immune system dysfunction. Types psoriasis-Plaque (psoriasis vulgaris), Pustular psoriasis, Nail Guttate Flexural Erythrodermic psoriasis. Activated T cells go into from circulation and lymph nodes rele...

conclusions aih in our region presents with advanced disease affecting predominantly children and adolescents. there is a genetic association of hla dr6 along with other alleles and antigens in our patients with aih. objectives the aim of this study was to evaluate the clinical profile of autoimmune hepatitis (aih), and determine the associated antigens and alleles by performing hla typing. pat...

major histocompatibility complex (mhc) class ii deficiency is a primary immunodeficiency disease characterized by abnormality of mhc class ii molecules surface expression on peripheral blood lymphocytes and monocytes. clinical manifestations include extreme susceptibility to viral, bacterial, and fungal infections but the immunodeficiency is not as severe as scid (severe combined immunodeficien...