exploration of natural products with antitumoral effects such as etoposide, tenioposide, camptothecin and paclitaxel from conifers provoked us to do some research on anti-tumoral activity of iranian medicinal plants. ten different species of iranian conifers aerial parts were collected across the country. the relative potency of methanolic extract were investigated on the inhibition of topoisom...

the cytotoxic activity of ethanolic extracts of thymus vulgaris, thuja orientalis and achillea millefolium was investigated on various growing tumor cell lines. mtt colorimetric assay was used for measuring the inhibition of cell proliferation. all of the three extracts showed a relatively dose-dependent inhibition of proliferation of human breast cancer (sk-br-3, mda-mb-435) and leukemia (u937...

Introduction: Nogo-A and Nogo receptor (NgR) are expressed in the subventricular zone (SVZ) stem cells. NgR plays critical inhibitory roles in axonal regeneration and remyelination. However, the role of NgR in SVZ niche behaviors in demyelination context is still uncertain. Here we investigated the effects of NgR inhibition on SVZ niche reaction in a local model of demyelination in adult mouse ...

the effect of vanillin on the corrosion behavior of aa6061 al alloy in 3.5% nacl solution wasinvestigated using potentiodynamic polarization and electrochemical noise (en) techniques. vanillinoffers interesting possibilities for corrosion inhibition due to its nontoxicity and high solubility inaqueous media. the best inhibition effect at 200 ppm vanillin was a marked characteristic of theinhibi...

the effect of repetitive electrical field stimulation and the response of the guinea-pig and rat ileal longitudinal muscle to single pulse stimulations was examined. single pulse field stimulation produced twitch contraction which was inhibited by repetitive field stimulation (10 hz, 40v, 0.5 msec for 5 m). this inhibition was largely, though never completely, reversed by naloxone. contractions...

background: the role of renin angiotensin system (ras) in ischemic/reperfusion (i/r) injuries is not fully elucidated. furthermore, it is not clear whether inhibition of ras by angiotensin-converting enzyme (ace) inhibitors has beneficial effects in terms of protecting the brain from i/r injuries. in this study enalapril is used as an ace inhibitor to evaluate the role of ras in i/r injuries in...

Vanillin offers interesting possibilities for corrosion inhibition because of its safe use and highsolubility in water. The effect of vanillin on the corrosion inhibition of AISI 304 stainless steel in0.5M H2SO4 solution has been studied using potentiodynamic polarization and electrochemicalimpedance spectroscopy (EIS). Furthermore, this paper demonstrates that the electrochemical noise(EN) tec...

Vanillin is an interesting corrosion inhibitor because of its safe use and high solubility inwater. The effect of vanillin on the corrosion inhibition of carbon steel in 1.0 Mhydrochloric acid solution has been studied using potentiodynamic polarization,electrochemical impedance spectroscopy (EIS) and electrochemical noise (EN) techniques.The effect of temperature on the rate of corrosion in th...