The objective of the present study was to assess intestinal permeability in patients with infection caused by Strongyloides stercoralis. Twenty-six patients (16 women and 10 men), mean age 45.9, with a diagnosis of strongyloidiasis were evaluated. For comparison, 25 healthy volunteers (18 women and 7 men), mean age 44.9, without digestive disorders or intestinal parasites served as normal contr...

Intestinal regeneration and tumorigenesis are believed to be driven by intestinal stem cells (ISCs). Elucidating mechanisms underlying ISC activation during regeneration and tumorigenesis can help uncover the underlying principles of intestinal homeostasis and disease including colorectal cancer. Here we show that miR-31 drives ISC proliferation, and protects ISCs against apoptosis, both during...

Background: Intestinal protozoa transmitted by food are the most common opportunistic parasites among the HIV+/AIDS patients. As, there is no report about prevalence of food-borne intestinal parasites in such patients in Yazd, so this study was performed to determine the prevalence of intestinal protozoa in the HIV+/AIDS patients in comparison with HIV- individuals. Methods: A case-control stu...

The most common and challenging gastrointestinal motility disorders in children include gastroesophageal reflux disease (GERD), esophageal achalasia, gastroparesis, chronic intestinal pseudo-obstruction, and constipation. GERD is the most common gastrointestinal motility disorder affecting children and is diagnosed clinically and treated primarily with acid secretion blockade. Esophageal achala...

Objective: The autoimmune diseases tend to coexist with diabetes mellitus type I (T1DM). The concomitance of these two types of diseases will lead to poor glycemic control beside their own complications. In this study the prevalence of thyroid disorder and celiac disease among T1DM patients in Yazd, Iran was evaluated. Materials and Methods: all the patients diagnosed as T1DM in Yazd younger t...

objectives: mentha longifolia l. (lamiaceae) is an annual herb that is used in the iranian traditional medicine for treating stomach and intestinal disorders. the purpose of this study was to determine the protective effect of m. longifolia on experimental diarrhea in a rat model. materials and methods: the antidiarrheal activity of essential oil of m. longifolia (20-80 mg/kg) was investigated ...

Intestinal alkaline phosphatase enzyme plays a pivotal role in the maintenance of intestinal mucosal barrier integrity with the detoxification capacity of lipopolysaccharide, the ligand of Toll-like receptor 4. The inappropriate immune responses and the damage of the mucosal barrier may contribute to the initiation of inflammatory bowel and celiac diseases. In the inflamed colonic mucosa of chi...

Nutritional management of patients with intestinal failure often includes the use oligomeric formulas. Implementing formulas in surgical maldigestion or malabsorption could be a nutritional strategy to included clinical protocols. We aim generate knowledge from survey focused on effectiveness therapy Delphi methodology. Each statement that reached an agreement consensus among participants was d...

Blastocystis hominis is an enteric protozoan. It frequently found in children and may cause chronic diarrhea. The present cross-sectional study was carried out during the period from October to December, 2021 Wasit Province of Iraq. A total 100 stool samples both gender different ages (two years 60 years) suffering primary gastro-intestinal disorders. All were examined microscopically by direct...

Studies of the initiation and maintenance of asthma and allergic inflammation implicate dysregulated interactions between mucosal epithelia and innate immune cells as the underlying cause of these disorders. The similarities of these responses with mucosal responses to parasitic intestinal worms may reveal pathways relevant to the perplexing rise of these chronic inflammatory disorders.