What is the critical period? Also known as the sensitive period, the critical period is a time during early postnatal life when the development and maturation of functional properties of the brain, its ‘plasticity’, is strongly dependent on experience or environmental influences. The concept of a critical period therefore plays an important role in the ageold nature versus nurture debate — to w...

We propose a new method for estimating the intrinsic dimension of a dataset by applying the principle of regularized maximum likelihood to the distances between close neighbors. We propose a regularization scheme which is motivated by divergence minimization principles. We derive the estimator by a Poisson process approximation, argue about its convergence properties and apply it to a number of...

The adult mammalian central nervous system exhibits restricted regenerative potential. Chen et al. (2011) and El Bejjani and Hammarlund (2012) used Caenorhabditis elegans to uncover intrinsic factors that inhibit regeneration of axotomized mature neurons, opening avenues for potential therapeutics.

In this work, we study the behavior of different algorithms that attempt to estimate the intrinsic dimension (ID) in metric spaces. Some of these algorithms were developed specifically for evaluating the complexity of the search on metric spaces, based on different theories related to the distribution of distances between objects on such spaces. Others were designed originally only for vector s...

The Ayurvedic concept of evolution of disease, based primarily in the understanding of the host-man, meaning of disease without losing sight of either the extrinsic or the intrinsic factors is comprehensive by itself. The modern descriptive methods has taken direction of possible correlation and elaboration of the Ayurvedic views.

The dentate gyrus of hippocampus has long been considered as a focal point for studies on mechanisms responsible for the development of temporal lobe epilepsy (TLE). Change in intrinsic properties of dentate gyrus granule cells (GCs) has been considered as an important factor responsible in temporal lobe seizures. In this study, we evaluated the intrinsic properties of GCs, during acute phase o...

The organic solvent extraction of Armillaria mellea showed different highly intrinsic fluorescent compounds either in rhizomorph or in hyphae (F , F , F , MF , MF and MF ). The characterization of ultraviolet and fluoro-spectrophotometry of these compounds has been exhibited. Thin layer chromatography and fluorescent spectrum of hyphae and rhizomorph indicated an additional compound (FH) ...

The dentate gyrus of hippocampus has long been considered as a focal point for studies on mechanisms responsible for the development of temporal lobe epilepsy (TLE). Change in intrinsic properties of dentate gyrus granule cells (GCs) has been considered as an important factor responsible in temporal lobe seizures. In this study, we evaluated the intrinsic properties of GCs, during acute phase o...

in this paper, we obtain two intrinsic integral inequalities of hessian manifolds.