Background: Given the variations in clinical presentation and physiopathological mechanisms in irritable bowel syndrome (IBS) subtypes, it is an acknowledged fact that the response to treatments can be disparate. Objective: To assess the effect of vitamin D on inflammatory cytokines (IL-17, IL-10, TNF-α), and biomarkers of oxidative stress (total antioxidant capacity (TAC), and malondialdehyde ...

Objective: Irritable Bowel Syndrome (IBS) is a chronic, disabling, and functional disorder of the gastrointestinal tract in the absence of identifiable structural disorder. The present study aimed to investigate the relationship between sensory processing sensitivity and life style with perceived stress considering mediating role of duration of syndrome in patients with IBS using structural equ...

Introduction: The gut microbiota is the microorganisms in digestive tract. They are mainly bacteria. play a very important role maintaining body's homeostasis. state of influenced by lifestyle including diet, stress and physical activity. In irritable bowel syndrome, there disorders composition intestinal microbiota. It also associated with disruption proper functioning gut-brain axis. Aim: aim...

Irritable bowel syndrome (IBS) is common. The symptom criteria for the diagnosis of IBS remain non specific. Similarly, pelvic inflammatory disease and endometriosis present with symptoms that may be similar to those of IBS. The site of pain, intermenstrual bleeding and exacerbation of symptoms by food may be able to help differentiate the two groups. However, there is still considerable overla...

The notion of food allergy in irritable bowel syndrome (IBS) is not new. However, recent evidence suggests significant reduction in IBS symptom severity in patients on elimination diets, provided that dietary elimination is based on foods against which the individual had raised IgG antibodies. These findings should encourage studies dissecting the mechanisms responsible for IgG production again...

Irritable bowel syndrome (IBS) is a very frequent functional gastrointestinal disorder characterized by recurrent abdominal pain or discomfort and alteration of bowel habits. The IBS physiopathology is extremely complex. Visceral hypersensitivity plays an important role in the pathogenesis of abdominal pain in both in vitro and in vivo models of this functional disorder. In order to obtain a ge...

Objective: To review the evidence supporting selected complementary and alternative medicine approaches used in the treatment of irritable bowel syndrome (IBS). Quality of evidence: MEDLINE (from January 1966), EMBASE (from January 1980), and the Cochrane Database of Systematic Reviews were searched until March 2008, combining the terms irritable bowel syndrome or irritable colon with complemen...

The role of diet in patients with Irritable Bowel Syndrome still remains empirical, as the underlying pathophysiologic disturbances of this disorder are not fully elucidated and randomised controlled trials are difficult to perform. The mainstey for dietary manipulation still remains the exclusion diets. The new, in this field is that the “forbidden” foods are fewer than in the past and the die...

irritable bowel syndrome (ibs) is the most prevalent functional gastrointestinal disorder noted in the general population worldwide. its chronic nature, signs and symptoms which vary periodically from mild to severe have many negative effects on the quality of life for the sufferer; therefore the appropriate treatment of these patients is highly important. patients should be informed by their d...