LIGNOCAINE has as yet been very little used for spinal anaesthesia, Adams (1956) alone having reported a series of cases in this country. This is probably because at the present time general anaesthesia is the rule and there is little interest in finding a better spinal analgesic. Having been very impressed by a sample of 5 per cent hyperbaric lignocaine (Xylocaine), it was decided to attempt a...

To determine whether airway receptors are responsible for the rapid, shallow breathing pattern seen in hypercapnic chronic obstructive lung disease, 10 patients underwent upper airway anaesthesia with inhaled lignocaine in a placebo controlled study. There was a significant reduction in breathing frequency after lignocaine (p less than 0.001) that was due to an increase in expiratory time (p le...

Pulsatile ocular blood flow, intraocular pressure, systemic blood pressure, and heart rate was measured in two groups of 15 patients. One received lignocaine 1.5 mgtkg intravenously prior to induction. There was a significant increase in intraocular pressure after suxamethonium, which was not associated with any rise in ocular blood flow. Both the IOP and ocular blood flow increased significant...

BACKGROUND The aim of this study was to compare the clinical efficacy of 5% lignocaine, 2.5% lignocaine, 0.5% bupivacaine and 0.25% bupivacaine in subarachnoid block for pelvic surgeries. METHODS 80 adult ASA grades I and II patients of either sex between the ages of 18-60 yrs, undergoing routine pelvic surgery of short duration were included in this prospective, randomized double blind study...

A small series of 20 patients treated this way is presented. These patients elected for this method for 2 main reasons, namely, financial constraint and a desire to be discharged home on the same day. Eighteen patients had third degree and two had fourth degree thrombosed haemorrhoids. The operations were performed under sedation in eight and under general anaesthesia in twelve patients. The pa...

Local anesthesia systemic toxicity (LAST) and anaphylaxis are the life-threatening adverse effects of lignocaine. Both have different presentations treatments. We report a case 35-year-old female who came to our Emergency Department (ED) with symptoms lethargy, drowsiness, difficulty breathing foreign body sensation metallic taste in throat which started 15 minutes after right shoulder injectio...

This study assessed the effects of inhaled lignocaine to reduce upper airway surface mechanoreceptor activity on 1) basal genioglossus and tensor palatini EMG, 2) genioglossus reflex responses to large pulses (∼10 cmH2O) of negative airway pressure, and 3) upper airway collapsibility in 15 awake individuals. Genioglossus and tensor palatini muscle EMG and airway pressures were recorded during q...