Aplasia Cutis Conginita (ACC) is a condition characterized by congenital absence of skin, usually on the scalp. ACC can occur as an isolated condition or in the presence of other congenital anomalies. Here we describe a case of a 16 days old baby girl with an isolated ACC of the scalp. Her elder two siblings have been diagnosed with ACC with concomitant cardiac or limb anomalies. The patient wa...

In complex lower limb trauma, the healthy recipient vessels can be far from the defect to be reconstructed due to the usually high-energy injury sustained. The use of vein grafts, either directly or in the form of arteriovenous loops, is the usual solution in these cases. In the vein graft donor-depleted patient, other options are required; the composite arteriovenous radial conduit flap may be...

We report a child with facial dysmorphic features, hypoplasia of the external genitalia, intestinal malrotation, congenital cardiac defect, and minor limb anomalies. Chromosome studies showed a recombinant chromosome 7, rec(7) dup p, resulting from a maternal pericentric inversion inv(7)(p15 q36). Thus, this child had partial trisomy 7p in addition to a small distal monosomy 7. The clinical fin...

The clinical case of a patient with a segmental humeral defect, in the context of an arthrogryposis congenita multiplex and morbid obesity, reconstructed with a pedicled segmental radial bone flap is reported. The use of the pedicled vascularized diaphyseal radial bone flap may be a useful technique for humerus reconstruction in patients with contraindication for microvascular bone transfers an...

BackgroundCongenital limb defects (CLD) occur when normal development of limbs is hampered during the intrauterine period. There a paucity literature regarding prevalence and pattern various congenital in India. The aim this study to assess CLD using Swanson classification state Uttarakhand, India.MethodsRetrospective over 6-year period was done. calculated by determining live births from birth...

Introduction: Soft tissue defect at ankle and foot region are very common following road traffic accident. Reconstruction in this is challenging to surgeon because of poor vascularity paucity available surrounding tissue. Purpose study evaluate various defect, advantage disadvantages different methods management, future prospective suitable method according defect.Materials Methods: Retrospecti...

Retinoic acid is a signaling molecule involved in the regulation of growth and morphogenesis during development. There are three types of nuclear receptors for all-trans retinoic acid in mammals, RAR alpha, RAR beta, and RAR gamma, which transduce the retinoic acid signal by inducing or repressing the transcription of target genes (Leid, M., P. Kastner, and P. Chambon. 1992. Trends Biochem. Sci...

BACKGROUND Large bone defect in infant or small patients has been little reported and the management of such a patient is difficult. Considering the little knowledge of this area, we present this special case of a successful single-cortex fibula graft for the treatment of a large tibia bone defect in a 2-year-old patient to share our experience. CASE SUMMARY A 2-year-old male patient presente...

OBJECTIVE The prevalence rate of all types of limb reduction defects in general and those that potentially are caused by vascular disruption in particular is needed to provide a baseline for the evaluation of infants who are exposed in utero to teratogens that cause vascular disruption. The objective of this study was to determine this prevalence rate. METHODS All infants with any limb defici...