It has already been reported that 1-methylnicotinamide (MNA+), a primary metabolite of nicotinamide (vitamin B3), possesses remarkable anti-inflammatory properties [3]. This communication shows that 1-methyl-N'-(hydroxymethyl)nicotinamide (MNAF+ can be regarded as MNA+ precursor able to release simultaneously formaldehyde. Therefore, MNAF+ can be viewed as a candidate for drug with the combined...

BACKGROUND MYCN amplification (MNA) in neuroblastoma is a strong indicator of poor prognosis. However, some MYCN nonamplified (non-MNA) cases show poor outcomes, and examining the status of the gene requires an operation, which may have surgical complications. Therefore, a new marker is needed to identify cases of non-MNA neuroblastomas with poor prognoses using less risky procedures. Aberrant ...

This cross sectional study was conducted to determine the validity of three screening tools, Mini Nutritional Assessment Short Form (MNA-SF), Malnutrition Risk Screening Tool for Community (MRST-C) and Malnutrition Risk Screening Tool for Hospital (MRST-H) among elderly people at health clinics. The screening tools were validated against anthropometric and functional assessments. The anthropome...

Virus neutralization assays measure neutralizing antibodies in serum and plasma, the plaque reduction test (PRNT) is considered gold standard for measuring levels of these many viral diseases. We have developed procedures PRNT, microneutralization assay (MNA) pseudotyped virus (PNA) severe acute respiratory syndrome coronavirus 2. The MNA offers advantages over PRNT by reducing time, allowing i...

Background: Malnutrition, loss of body weight, muscle and fat mass wasting are common in patients with Parkinson's disease, and are associated with disability, longer length of hospital stay, impaired immune system and increased risk of mortality. The aim of this study was to assess the nutritional status in patients with Parkinson's disease and its relation to the severity of the disease. &...

(3-Aminopropyl) triethoxysilane (APTES) modified magnetic graphene oxide was synthesized and applied in the adsorption of three heavy metals, Pb(II), Cd(II) Ni(II) from aqueous solution. An approach to prepare GO adopted by using (3-aminopropyl) as a functionalizing agent on nanosilica coupled with form Fe3O4@SiO2–NH2/GO nanocomposite. FT-IR, XRD, BET, UV, VSM, SAXS, SEM TEM were used character...

Introducción. La población peruana está envejeciendo y ello viene asociado al deterioro de la salud. Dicho proceso puede ser retardado o acelerado dependiendo del estado nutricional. Objetivos. Determinar los factores asociados riesgo nutricional en un grupo personas adultas mayores. Métodos. Se encuestaron 265 adultos mayores, libres cognitivo capaces comunicarse, atendidos centros atención pr...

The fluctuations of three-dimensional molecular conformations of a molecule in different environments play critical roles in many important chemical and biological processes. X-ray diffraction (XRD) techniques and nuclear magnetic resonance (NMR) methods are routinely applied to monitor the molecular conformations in condensed phases. However, some special requirements of the methods have preve...