Fahr's disease is a rare syndrome characterized by symmetrical and bilateral intracranial calcifications. We report a 21-year-old male who presented with aggression, talkativeness, restlessness, and insomnia of recent onset. His neurological examination was normal. Mental status examination and clinical investigation revealed mania. Brain revealed symmetrical large areas and foci of calcificati...

Acute Mania Quetiapine XR (FDA approved for the treatment of acute mania) monotherapy has been shown to be more effective than placebo in treating acute mania with improvement starting at day 4. Aripiprazole adjunctive therapy was more effective than placebo adjunctive therapy in treating manic symptoms in BD manic patients with inadequate response to lithium or divalproex in a 6 week trial. Ol...

Neuropsychiatric symptoms (NPS) are common in the middle to late stages of Alzheimer’s dementia (AD), but can also present in the Mild Cognitive Impairment (MCI) phase. Since the pathophysiology of AD involves deficits in central cholinergic neurotransmission, cholinesterase inhibitors (CHEIs) are effective in treating its cognitive symptoms. Interestingly, case studies have reported the onset ...