The purpose of this research was to prepare a floating matrix tablet containing domperidone as a model drug. Polyethylene oxide (PEO) and hydroxypropyl methylcellulose (HPMC) were evaluated for matrix-forming properties. A simplex lattice design was applied to systemically optimize the drug release profile. The amounts of PEO WSR 303, HPMC K15M and sodium bicarbonate were selected as independen...

‎let $g$ be a graph with vertex set $v(g)$ and edge set $x(g)$ and consider the set $a={0,1}$‎. ‎a mapping $l:v(g)longrightarrow a$ is called binary vertex labeling of $g$ and $l(v)$ is called the label of the vertex $v$ under $l$‎. ‎in this paper we introduce a new kind of graph energy for the binary labeled graph‎, ‎the labeled graph energy $e_{l}(g)$‎. ‎it depends on the underlying graph $g$...

Interior-point methods in semidefinite programming (SDP) require the solution of a sequence of linear systems which are used to derive the search directions. Safeguards are typically required in order to handle rank-deficient Jacobians and free variables. We generalize the primal-dual regularization of Friedlander and Orban (2012) to SDP and show that it is possible to recover an optimal soluti...

Here we present a new approach to calculating the square root of a quadratic matrix. Actually, the purpose of this article is to show how the Cayley-Hamilton theorem may be used to determine an explicit formula for all the square roots of $2times 2$ matrices.

different methods have been proposed for finding the non-negative solution of fully fuzzy linear system (ffls) i.e. fuzzy linear system with fuzzy coefficients involving fuzzy variables. to the best of our knowledge, there is no method in the literature for finding the non-negative solution of a ffls without any restriction on the coefficient matrix. in this paper a new computational method is ...

A partial pre-distance matrix A is a matrix with zero diagonal and with certain elements fixed to given nonnegative values; the other elements are considered free. The Euclidean distance matrix completion problem chooses nonnegative values for the free elements in order to obtain a Euclidean distance matrix, EDM. The nearest (or approximate) Euclidean distance matrix problem is to find a Euclid...