It is currently believed that melamine ingestion can lead to insoluble crystals in an animal's urinary system with subsequent physical obstruction or bladder carcinoma. However, whether melamine can cause injury of other tissues and organs in humans is yet unknown. In this study, we encountered 3 affected children with liver lesions, 2 males and 1 female, and detailed their clinical characteriz...

Based on melamine binding-triggered triplex formation and subsequent activation of Mg(2+)-dependent DNAzymes, a novel strategy for DNAzyme regulation was proposed and developed for melamine recognition.

In this work, a molecularly imprinted polymer (MIP) coated stir bar was prepared using a self-designed polytetrafluoroethylene (PTFE) mold and in situ polymerization, with cyromazine as the dummy template for the target melamine. The prepared MIP coated stir bar presented a uniform and porous surface as well as good chemical stability and selectivity for melamine. Based on it, a method of MIP c...

The melamine contaminated milk powder contamination scandal occurred in China in 2008. Its main consequences so far have been urinary stone formation in children with associated renal damage and increased child mortality. Eight years have passed, but food safety issues still remain of concern in the daily lives of millions of Chinese. Vigilance is required to ensure no recurrence of such food s...

Since the melamine-contamination event happened in September 2008, there have been lots of studies about melamine toxicity, but very limited studies focused on central nervous system (CNS). In the present study, we investigated the effects of melamine (5x10(-4), 5x10(-5) and 5x10(-6)g/ml) on voltage-gated sodium channels (VGSCs) in hippocampal CA1 neurons using whole-cell patch-clamp recordings...

In this study a new method by Application of graphene oxide Nano sheets– Melamine –TioOxalic acid composite was exhibited as adsorbent for the elimination of toxic mercury (II) ions from aqueous solutions. The combine has the authority to adsorb the organic and inorganic combines. Through the immobilization of Melamine-TioOxalic acid (MTO) onto graphene oxide nanosheets, the desired composite w...

The aggregation and supramolecular chirality of the interfacial assemblies of an achiral phthalcyanine derivative, zinc 2,3,9,10,16,17,23,24-octakis(octyloxy)-29 H,31 H-phthaloxyanine (ZnPc), were investigated, and a surface pressure dependent behavior was observed. It was found that ZnPc could be spread as a Langmuir film on water surface and transferred onto solid substrates by the horizontal...

Melamine is an adulterant commonly found in milk, as it can increase the nitrogen content. Therefore, its apparent protein content, resulting in a better market price. Melamine adulteration can be fatal, as was highlighted in 2008 when six infants died due to melamine adulteration in milk powder and thousands were sickened in China. Consequently, there have been stricter regulations globally an...