ADHD (attention hyperactivity disorder) is a polygenetic disorder with various candidate genes. At this time, more than thirty dopaminergic, noradrenergic, serotonergic and GABA-ergic genes are known. The research of only some candidate genes (DRD4, DAT, DRD5, DBH, 5HTT, HTR1B and SNAP25) brought relatively consistent results confirming the heredity of ADHD syndromes. The results of research of...

OBJECTIVE We investigated the effects of duloxetine on the plasma levels of catecholamine metabolites and serum brain-derived neurotrophic factor (BDNF) in 64 patients with major depressive disorder (MDD). METHODS Major depressive episode was diagnosed using the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders-fourth edition (DSM-IV) according to the...

Noradrenergic and GABA systems may be involved in mania, but there is little information about relationships between the function of these systems and response to specific antimanic treatments. We investigated relationships between indices of catecholamine or GABA system function, pretreatment mania severity and antimanic response to divalproex, lithium, or placebo. Plasma GABA and urinary excr...

Biogenic amine metabolism in the central nervous system of 9 children with Tourette syndrome was evaluated by quantitation of their metabolites in cerebrospinal fluid by a gas chromatographic/mass spectrometric method. Homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA), and 3-methoxy-4-hydroxyphenylethylene glycol (MHPG) were measured in CSF before and after oral administration of pro...

This study involved pediatric cases with Acute fulminant hepatocellular failure (AFHF) put on conventional therapy at the Hospital for children, Madras. In these cases, the biogenic amine status was studied at the time of admission, during therapy and at the time of recovery in responders. The CSF 5-HT, 5-hydroxyindoleacetic acid (5-HIAA) and Homovanillic acid (HVA), blood 5-HT and 5-HIAA, and ...

introduction: the objective of this study was, wastewater quality investigation and removal efficiency of contaminants from the wastewater tile factory by using  coagulants includes ferric chloride, ferric sulfate and ferrous, aluminum sulfate and poly aluminum chloride in order to reuse it in the processing line. methods: this is an applied study. with regard to shiftwork schedules of the fact...

background: untreated leachate is being discharged into the environment in many countries worldwide. leachate treatment methods have not been unified so far due to the variable composition of leachate. moreover, the lack of appropriate treatment and disposal of leachate causes environmental pollution. this study aimed to compare removal efficiency of chemical oxygen demand (cod) and total suspe...

Sulfate-bearing soils, which causes many engineering problems, e.g., cracking, collapse, and pavement layer settlement, are often encountered in the construction of pavements. Ground granulated blast furnace slag (GGBS)-magnesia (MgO) has been regarded as an effective curing agent treatment sulfate-bearing soil containing gypsum. However, field soils usually include other forms sulfates, such s...

Bemmel, A.L. van and R.H. van den Hoofdakker. Maintenance of therapeutic effects of total sleepdeprivation by means of limitation of subsequent sleep. Abstr. 5th ESRS Congress, Amsterdam,1980.Smeets, E.H.J. and A.L. van Bemmel. Phase-advance of urinary MHPG excretion in normals anddepressives, Abstr. 11th CINP Congress, Florence, 1984.Bemmel, A.L. van, R. van Diest and J.H.M...