A HYPOCHROMIC microcytic anemia in children was first described by Cooley and Lee’ in 1915. Later, milder forms of this condition were recorded. 2, 3 The highest incidence of the disease has been shown to occur in persons of Mediterranean stock (Italians, Greeks, Syrians, and Armenians). However, cases have been reported in individuals of English, German, Spanish, Egyptian, Chinese,4 and Negro5...

T he study of anemia and iron deficiency in 9-month-old James Bay Cree infants reported in this issue (page 323) 1 raises 2 interesting and provocative questions. First, what is anemia in this age group? Second , how well is a breast-fed 9-month-old infant protected against iron deficiency? Commonly used norms were derived from populations of nonindigenous white children living near sea level, ...

A HYPOCHROMIC microcytic anemia in children was first described by Cooley and Lee’ in 1915. Later, milder forms of this condition were recorded. 2, 3 The highest incidence of the disease has been shown to occur in persons of Mediterranean stock (Italians, Greeks, Syrians, and Armenians). However, cases have been reported in individuals of English, German, Spanish, Egyptian, Chinese,4 and Negro5...

Some routine red blood cell (RBC) measurements and indexes (count, mean volume, volume dispersion, and mean hemoglobin [HGB] concentration) can be used to differentiate iron deficiency from heterozygous beta-thalassemia. A number of formulas that incorporate two or more of these measurements have been described to amplify such differences. The H*1 hematology analyzer directly measures volume an...

Abstract Introduction Asymptomatic microcytosis may be a prelude to microcytic hypochromic anemia of varied causes. Evaluation red cell indices help delineate cases needing further investigation like hemoglobin high-performance liquid chromatography (Hb-HPLC). In addition, markers iron homeostasis will confirm iron-deficient erythropoiesis (IDE)/iron deficiency (IDA). Materials and Methods This...

BACKGROUND Diagnosing canine immune-mediated haemolytic anaemia (IMHA) is often challenging because all currently available tests have their limitations. Dogs with IMHA often have an increased erythrocyte osmotic fragility (OF), a characteristic that is sometimes used in the diagnosis of IMHA. Since the classic osmotic fragility test (COFT) is time-consuming and requires specialized equipment, ...