Abstract Background: The study was established to define the prevalence of neonatal microcytosis and to estimate the incidence rate of alpha-thalassemia as its leading cause, in Tehran, Iran. Materials and Methods: Overall, 800 neonates were selected from two populations of newborns and admitted neonates. Three hundred and sixty-one cord blood samples were obtained from deliveries in Ma...

BACKGROUND Red cell microcytosis is a common abnormality detected in a full blood count, which often prompts clinicians to investigate further for a cause. In the absence of iron deficiency and anaemia of chronic disease, the differential diagnosis includes β-thalassaemia trait and α-thalassaemia trait. METHODS We investigated the contribution of α-thalassaemia trait in South African subjects...

AIMS Hypochromic microcytic anaemia is the hallmark phenotype of thalassaemia. Current phenotypical tests do not provide a diagnosis in a small proportion of patients with red blood cell microcytosis. We aim to evaluate the genetic basis of red cell microcytosis in these cases in our Chinese population. METHODS We identified from a large cohort of 1684 unselected requests for thalassaemia tes...

background :identification of α thalassemia (α thal) a common cause of microcytosis during neonatal periods is an important step prevent unnecessary interventions. thus, low the mean corpuscular volume (mcv) and the mean corpuscular hemoglobin (mch) may consider as α-thalassemia key detection points. the present study aimed to determine the prevalence of microcytosis among neonates who born in ...

abstract background: the study was established to define the prevalence of neonatal microcytosis and to estimate the incidence rate of alpha-thalassemia as its leading cause, in tehran, iran. materials and methods: overall, 800 neonates were selected from two populations of newborns and admitted neonates. three hundred and sixty-one cord blood samples were obtained from deliveries in mahdieh ho...

BACKGROUND Identification of α thalassemia (α thal) a common cause of microcytosis during neonatal periods is an important step prevent unnecessary interventions. Thus, low the mean corpuscular volume (MCV) and the mean corpuscular hemoglobin (MCH) may consider as α-thalassemia key detection points. The present study aimed to determine the prevalence of microcytosis among neonates who born in T...

Aim and Objective: To evaluate usefulness of Single Tube Osmotic Fragility Test (SOFT) for detection of microcytosis and its further application for thalassemia trait screening. Background: Iron deficiency and thalassemia are common causes of microcytic anaemia in Pakistan. Easy microcytosis screening is necessary at a low resourced country like Pakistan, so that further investigations speciall...

Background. Elevated middle cerebral artery peak systolic velocity (MCA-PSV) has been reported in nonanemic fetuses following fetal transfusion, and has been attributed to a major population of red blood cells (RBCs) with an adult mean corpuscular volume (MCV) in the fetal circulation. Reported here is an analogous case of elevated MCA-PSV with a normal fetal hematocrit and relative fetal micro...