نتایج جستجو برای: mrsa activity
تعداد نتایج: 1143134 فیلتر نتایج به سال:
Background: Plants have been the basis for many medicinal compounds that are used in modern-day medicine, screening plants bioactive is a way of identifying and developing new antimicrobials less expensive with improved safety efficacy. Objective: The objective this study was to investigate vitro antimicrobial activity Azadirachta indica (neem) using leaf extracts Ethanol, Petroleum ether, Ethy...
The resistance of pathogenic bacteria to antibiotics is increasing due with incorrect doses, wrong diagnostics, and the target. Bacteria that have been resistant several are called multi-drug organisms (MDRO) bacteria. Bacterial some requires alternative herbal treatments, one which Chromolaena odorata L. Research must therefore be conducted on antibacterial activity ethanol extract fraction C....
Novel classes of antimicrobials are needed to address the challenge of multidrug-resistant bacteria such as methicillin-resistant Staphylococcus aureus (MRSA). Using the architecture of the MRSA interactome, we identified pyruvate kinase (PK) as a potential novel drug target based upon it being a highly connected, essential hub in the MRSA interactome. Structural modeling, including X-ray cryst...
Staphylococcus aureus is an opportunistic pathogen and remains a common cause of burn wound infections. Different studies have shown that entrapment of plant-derived compounds into liposomes could increase their anti-Staphylococcus aureus activity. Silymarin is the bioactive extract from the known plant Silybum marianum L. The objective of this study was to evaluate efficacy of silymarin in fre...
Staphylococcus aureus is an opportunistic pathogen and remains a common cause of burn wound infections. Different studies have shown that entrapment of plant-derived compounds into liposomes could increase their anti-Staphylococcus aureus activity. Silymarin is the bioactive extract from the known plant Silybum marianum L. The objective of this study was to evaluate efficacy of silymarin in fre...
New agents are needed with the increasing prevalence of multidrug-resistant (MDR) bacteria. Identification plants activity against MDR bacteria is importance. The antimicrobial commercially available Graviola preparations 38 clinical and laboratory isolates, representing drug-sensitive Gram positive negative bacteria, was measured by broth microdilution. Commercially fruit, as well leaves/stems...
There is an urgent need for new antibiotics to treat hospital- and community-associated methicillin-resistant Staphylococcus aureus (MRSA) infections. Previous work has indicated that both terrestrial and marine-derived members of the napyradiomycin class possess potential anti-staphylococcal activities. These compounds are unique meroterpenoids with unusual levels of halogenation. In this pape...
استافیلوکوک اورئوس مقاوم به متی سیلین (mrsa) یکی ازپاتوژن های اصلی مسئول عفونت های بیمارستانی و غیربیمارستانی محسوب می شود. هدف این تحقیق بررسی شیوع nasal mrsa در بیمارستان ایرانمهر هنگام پذیرش بیماران در مقایسه با هنگام ترخیص بود.یک صد بیمار به صورت تصادفی برای این مطالعه انتخاب شدند. پس از توجیهات اولیه و ثبت اطلاعات بالینی اولیه و جمعیتی، با سوآپ استریل از مجرای قدامی بینی آنان نمونه گیری در...
Synthesis of new tricyclic carbapenems (trinems) with a pyrrolidinyl moiety at the C-4 position of the tricyclic ring and their antimicrobial activities were studied. These trinems showed potent activities against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA). Among them, (4R)-[(S)-pyrrolidin-3-ylthiomethyl]trinem (14a) exhibited good activity against MRSA ...
Actinobacteria are known to produce various secondary metabolites having antibiotic effects. This study assessed the antimicrobial potential of actinobacteria isolated from the rhizosphere of Caesalpinia pyramidalis Tul. from the Caatinga biome. Sixty-eight actinobacteria isolates were evaluated for antimicrobial activity against different microorganisms by disk diffusion and submerged fermenta...
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