Enterococcus faecalis is a Gram-positive, opportunistic, pathogenic bacterium that causes a significant number of antibiotic-resistant infections in hospitalized patients. The development of antibiotic resistance in hospital-associated pathogens is a formidable public health threat. In E. faecalis and other Gram-positive pathogens, correlations exist between lipid composition and antibiotic res...

Antibiotic resistance is a global public health problem that requires our attention. Indiscriminate antibiotic use is a major contributor in the introduction of selective pressures in our natural environments that have significantly contributed in the rapid emergence of antibiotic-resistant microbial strains. The use of probiotics in lieu of antibiotic therapy to address certain health conditio...

Efflux pump genes and proteins are present in both antibiotic-susceptible and antibiotic-resistant bacteria. Pumps may be specific for one substrate or may transport a range of structurally dissimilar compounds (including antibiotics of multiple classes); such pumps can be associated with multiple drug (antibiotic) resistance (MDR). However, the clinical relevance of efflux-mediated resistance ...

Background: The increased use of antibiotics in recent times has resulted in the development of resistance to antibiotics. The significant clinical implication of resistance has led to heightened interest in the study of bacterial resistance. Purpose: This study was carried out to evaluate the effects of antibiotic-combinations against some community isolates of multiple antibiotic-resistant St...

OBJECTIVES To determine the structure of the resistance region in an IncHI1 plasmid conferring resistance to multiple antibiotics, including gentamicin, recovered from a Salmonella enterica serovar Typhimurium isolate from a horse. METHODS Plasmids were recovered by conjugation. The plasmid type, resistance genes and their context were identified by PCR, cloning, hybridization and DNA sequenc...

Antibiotic resistance among gram-negative bacilli shows no signs of abatement. Resistance of Pseudomonas aeruginosa, Acinetobacter baumannii, and the Enterobacteriaceae to multiple antibiotic classes is a growing clinical problem worldwide [1]. Two trends are particularly noteworthy. First, there has been increased recognition of successful antibiotic-resistant clones appearing in multiple geog...

Introduction: Pseudomonas aeruginosa is an opportunistic pathogen of clinical importance, particularly in immunocompromised and burn patients. This bacterium is becoming resistant to many antibiotics via intrinsic or acquired mechanisms. Mutations in anti-mutator genes, such as pfpI, can be a potential intrinsic mechanism of antibiotic resistance. This study aimed to evaluate the possible effec...

Salmonella and Vibrio species were isolated and identified from Litopenaeus vannamei cultured in shrimp farms. Shrimp samples showed occurrence of 3.3% of Salmonella and 48.3% of Vibrio. The isolates were also screened for antibiotic resistance to oxolinic acid, sulphonamides, tetracycline, sulfamethoxazole/trimethoprim, norfloxacin, ampicillin, doxycycline hydrochloride, erythromycin, chloramp...

the present study aimed to evaluate the antibiotic resistance pattern of escherichia coli strains isolatedfrom animals to ascertain the levels of antibiotic resistance pervasiveness. a total of 28 e. coli strains wereisolated from faecal samples and the antibiotic resistance pattern of e. coli strains was determined by meansof disc diffusion assay. the resistance pattern determined for all stra...

Industrially polluted streams and rivers are of great concern to public health officials and environmental regulators. A lesser known problem is that some water resources have become reservoirs of antibiotic resistance genes that can, under natural conditions, be transferred to water-borne pathogens. The current opinion in the scientific community is that the rapid and continuing increase in an...