The aim of this study was to determine that low-intensity pulsed ultrasound (LIPUS) at an intensity 140 mW/cm2 promotes functional and histologic improvements in sciatic nerve crush injury a rat model investigate changes over time relevant growth factors receptors, exploring the mechanism LIPUS recovery process after injury. Toe angle toe-off phase, regenerative axonal length, myelinated fiber ...

The features of unlesioned and lesioned trochlear nerves of goldfish have been examined electron microscopically. Lesioned nerves were studied between 1 and 107 days after cutting or crushing the nerve. Unlesioned nerves contained, on average, 77 myelinated axons and 19 unmyelinated axons. The latter were found in 1-2 fascicles per nerve. A basal lamina surrounded each myelinated axon and fasci...

The brain consists of a complex network of axons, transmitting electrical impulses between interconnected neurons across distances that range from fractions of millimeters to meters. Myelinated axons, or nerve fibers, are axons that are wrapped by a myelin sheath, serving as an electrical insulation that increases the propagation speed of the signal along the nerve fiber while conserving the en...

The presence of intact paranodal junctions on myelinated axons in the CNS and PNS is crucial for both myelin sheath attachment and saltatory impulse conduction. The axonal glycoprotein contactin-associated protein (Caspr) is expressed in the paranodal region and plays an important role in the creation and maintenance of these adhesive junctions. In the present study, antibodies to Caspr were us...

The myelin-associated glycoprotein (MAG) is an integral membrane glycoprotein that is located in the periaxonal membrane of myelin-forming Schwann cells. On the basis of this localization, it has been hypothesized that MAG plays a structural role in (a) forming and maintaining contact between myelinating Schwann cells and the axon (the 12-14-nm periaxonal space) and (b) maintaining the Schwann ...