نتایج جستجو برای: nanoliposome
تعداد نتایج: 140 فیلتر نتایج به سال:
Objective(s): Dendritic cells (DCs) play a critical role in activation of T cell responses. Induction of type1 T helper (Th1) immune response is essential to generate protective immunity against cutaneous leishmaniasis. The intrinsic tendency of liposomes to have interaction with antigen-presenting cells is the main rationale to utilize liposomes as antigen carriers. In the present study, the e...
Staphylococcus aureus is an opportunistic pathogen and remains a common cause of burn wound infections. Different studies have shown that entrapment of plant-derived compounds into liposomes could increase their anti-Staphylococcus aureus activity. Silymarin is the bioactive extract from the known plant Silybum marianum L. The objective of this study was to evaluate efficacy of silymarin in fre...
We aimed to optimize the formulation of C3G nanoliposomes using response surface methodology. Additionally, we evaluated the stability, particle change, and encapsulation efficiency (EE) of C3G nanoliposomes under different temperatures and storage durations, as well as in simulated gastrointestinal juice (SGF) and simulated intestinal fluid. The morphology of C3G nanoliposomes was observed by ...
Abstract A phase I/IIa dose escalation trial was initiated to determine the safety and recommended II (RP2D) of 186RNL in patients with recurrent glioma. Liposomal rhenium-186 (186RNL) is a source high energy beta particles gamma photons attractive properties for brain CED.Patients biopsy proven glioma had computerized treatment planning placement up 4 intracranial catheter(s). Each patient rec...
Gastric carcinoma (GC) has high incidence and mortality rates in China. Surgery and chemotherapy are the main treatments. Photodynamic therapy (PDT) has become a new treatment modality, appearing in recent experimental studies and clinical trials in various tumors. This study explores the combined effect of gene transfection with PDT on GC cells using aloe emodin (AE)-encapsulated nanoliposomes...
Background: The application of natural compounds including green tea extract (GTE) in food and pharmaceutical industries is limited. Encapsulation in nanoliposomes could be used as a delivery system to protect these compounds during processing and storage. Objective: In this study encapsulation of green tea extract in nanoliposomes and evaluation of its antibacterial, antioxidant and prebiot...
Background: Ducrosia anethifolia (DC.) Boiss is native to Iran and its essential oil has cytotoxic effects. Objective: Herbal Essences have limited application due to instability. In this research, nanoliposome containing Ducrosia essential oil has been studied for abundance and size distribution to enhance the essential oil stability for use in drug delivery systems. Methods: Essential oil was...
Purpose: Resistance to platinum chemotherapy remains a significant problem in ovarian carcinoma. Here, we examined the biological mechanisms and therapeutic potential of targeting a critical platinum resistance gene, ATP7B, using both in vitro and in vivo models. Experimental Design: Expression of ATP7A and ATP7B was examined in ovarian cancer cell lines by real-time reverse transcription-PCR a...
Background: Antimitotic drugs represent some of the most popular vascular disrupting agents used today in the fight against cancer. Colchicine is the first known antimitotic alkaloid. The drug binds to tubulin proteins and depolymerizes microtubules. Despite the impressive therapeutic activity as an antimitotic agent, colchicine is fatally toxic when administered to cancer patients intravenousl...
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