OBJECTIVES To evaluate the changes in types of medications prescribed for pain before and after withdrawal of certain selective cyclooxygenase 2 (COX-2) inhibitors in 2004 and to determine whether there was an association with fall events in elderly adults with a diagnosis of osteoarthritis (OA). DESIGN A nested case-control design using electronic medical records compiled between 2001 and 20...

(3) first described a syndrome, commonly referred to as "writhing", which was induced in rodents by the intraperitoneal injection of various chemical agents. Collier et al. (4) have recently reported experiments on the abilities of various sub stances, including some occurring in tissues and causing pain in man, to induce abdominal construction in mice. Many investigators have described the non...

In the description of parental psychopathology in narcotic dependence, emphasis has hitherto largely lain on the identification of addictogenic characteristics rather than on the identification of psychological distress. In an attempt to remedy the situation, we compared the parents of 21 male narcotic dependant patients with an equal number of matched controls. Using the General Health Questio...

The United Nations Convention against Illicit Traffic in Narcotic Drugs and Psychotropic Substances devotes Article 17 to combating illicit traffic by sea. It establishes a mechanism for the suppression of such activities when they are carried out outside territorial sea States accordance with International Law Sea. Among tools envisaged is possibility Parties establish bilateral multilateral a...

In the editorial note on Controlled Drugs which I contributed to the issue of September 9 (Canad. M. A. J., 85: 661, 1961), I find that I have overstated the case for written prescriptions for the amphetamines and the barbiturates. Pharmacists may dispense Controlled Drugs on the strength of a prescription given verbally by a physician as well as by a prescription in writing. The pharmacist mus...

BACKGROUND Ketorolac's efficacy as a postoperative analgesic has been shown to be comparable to that of narcotic analgesics, but with significantly fewer narcotic-related adverse events. OBJECTIVE To assess whether the choice of postoperative analgesic, narcotic or ketorolac, has an impact on healthcare resource utilization and cost durng inpatients' recovery period. DESIGN Retrospective, m...